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Alejandro García-Carrancá
Researcher at National Autonomous University of Mexico
Publications - 144
Citations - 4637
Alejandro García-Carrancá is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Cervical cancer & Cancer. The author has an hindex of 34, co-authored 136 publications receiving 3779 citations.
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Journal ArticleDOI
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches.
Karen Griselda de la Cruz-López,Leonardo Josué Castro-Muñoz,Diego O. Reyes-Hernández,Alejandro García-Carrancá,Joaquín Manzo-Merino +4 more
TL;DR: The goal of this review is to expose that lactate is not only a secondary product of cellular metabolic waste of tumor cells, but also a key molecule involved in carcinogenesis as well as in tumor immune evasion.
Journal ArticleDOI
Asian-American Variants of Human Papillomavirus 16 and Risk for Cervical Cancer: a Case–Control Study
Jaime Berumen,Rosa M. Ordoñez,Eduardo Lazcano,Jorge Salmerón,Silvia C. Galvan,Ruth A. Estrada,Elsa Yunes,Alejandro García-Carrancá,Guillermo Gonzalez-Lira,Angeles Madrigal-de la Campa +9 more
TL;DR: The high frequency of HPV16 AA variants, which appear to be more oncogenic than E variants, might contribute to the high incidence of cervical cancer in Mexico.
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Cervical Microbiome and Cytokine Profile at Various Stages of Cervical Cancer: A Pilot Study.
Astride Audirac-Chalifour,Kirvis Torres-Poveda,Margarita Bahena-Román,Juan Téllez-Sosa,Jesús Martínez-Barnetche,Bernardo Cortina-Ceballos,Guillermina López-Estrada,Karina Delgado-Romero,Ana I. Burguete-García,David Cantú,Alejandro García-Carrancá,Vicente Madrid-Marina +11 more
TL;DR: The results suggest that the cervical microbiota may be implicated in cervical cancer pathology, and further cohort studies are needed to validate these findings.
Journal ArticleDOI
Mexican medicinal plants used for cancer treatment: pharmacological, phytochemical and ethnobotanical studies.
Angel Josabad Alonso-Castro,María Luisa Villarreal,Luis A. Salazar-Olivo,Maricela Gómez-Sánchez,Fabiola Domínguez,Alejandro García-Carrancá +5 more
TL;DR: A review of Mexican medicinal flora in terms of ethnobotanical, pharmacology, and chemistry of natural products related to anticancer activity indicates that it is time to increase the number of experimental studies and to conduct clinical trials with those Mexican plants and its active compounds selected by in vitro and in vivo activities.
Journal ArticleDOI
Cancer-initiating cells derived from established cervical cell lines exhibit stem-cell markers and increased radioresistance
Jacqueline López,Adela Poitevin,Veverly Mendoza-Martínez,Carlos Pérez-Plasencia,Alejandro García-Carrancá +4 more
TL;DR: Describing a self-renewing subpopulation of CICs found among four well known human cancer-derived cell lines and found that they express characteristic markers of stem cell, EMT and radioresistance suggests that specific detection and targeting of C ICs could be highly valuable for the therapy of tumors from the uterine cervix.