A
Alessandra Del Giudice
Researcher at Sapienza University of Rome
Publications - 49
Citations - 376
Alessandra Del Giudice is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 8, co-authored 29 publications receiving 175 citations.
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Journal ArticleDOI
Bile Salts: Natural Surfactants and Precursors of a Broad Family of Complex Amphiphiles.
Maria Chiara di Gregorio,Leana Travaglini,Alessandra Del Giudice,Jacopo Cautela,Nicolae Viorel Pavel,Luciano Galantini +5 more
TL;DR: The unconventional amphiphilic molecular structure imparts specific features to BSs and derivatives that can be exploited in the formulation of capsules, drug carriers, dispersants, and templates for the synthesis of nanomaterials.
Journal ArticleDOI
Arabidopsis and Chlamydomonas phosphoribulokinase crystal structures complete the redox structural proteome of the Calvin-Benson cycle.
Libero Gurrieri,Alessandra Del Giudice,Nicola Demitri,Giuseppe Falini,Nicolae Viorel Pavel,Mirko Zaffagnini,Maurizio Polentarutti,Pierre Crozet,Christophe H. Marchand,Julien Henri,Paolo Trost,Stéphane D. Lemaire,Francesca Sparla,Simona Fermani +13 more
TL;DR: Structural comparisons with ancient PRKs indicate that the presence of flexible regions close to regulatory cysteines is a unique feature that is shared by TRX-dependent CB cycle enzymes, suggesting that the evolution of the PRK structure has resulted in a global increase in protein flexibility for photosynthetic eukaryotes.
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A fluorescence study of the loading and time stability of doxorubicin in sodium cholate/PEO-PPO-PEO triblock copolymer mixed micelles.
Elisamaria Tasca,Alessandra Del Giudice,Luciano Galantini,Karin Schillén,Anna Maria Giuliani,Mauro Giustini +5 more
TL;DR: Doxorubicin hydrochloride uptake in the micellar systems formed by sodium cholate (NaC) and the PEO100PPO65PEO100 (F127) copolymer, prepared with different mole ratios was studied.
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Time-Dependent pH Scanning of the Acid-Induced Unfolding of Human Serum Albumin Reveals Stabilization of the Native Form by Palmitic Acid Binding
TL;DR: The approach solved the problem of realizing a continuous, homogeneous, and tunable acidification with simultaneous characterization applicable to study processes triggered by a pH decrease, and found that when binding the ligand, the native conformation was favored up to lower pH values.
Journal ArticleDOI
Transition from molecular- to nano-scale segregation in a deep eutectic solvent - water mixture
Matteo Busato,Valerio Di Lisio,Alessandra Del Giudice,Pierpaolo Tomai,Valentina Migliorati,Luciano Galantini,Alessandra Gentili,Andrea Martinelli,Paola D'Angelo +8 more
TL;DR: In this paper, the changes upon water addition in the nanostructure of a deep eutectic solvent (DES) formed by choline chloride (ChCl) and sesamol in 1:3 ratio have been studied by means of small and wide-angle X-ray scattering (SWAXS), ATR-FTIR spectroscopy and molecular dynamics (MD) simulations.