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Alessandro Frati
Researcher at Sapienza University of Rome
Publications - 177
Citations - 3418
Alessandro Frati is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Medicine & Autophagy. The author has an hindex of 27, co-authored 144 publications receiving 2639 citations. Previous affiliations of Alessandro Frati include Istituto Superiore di Sanità.
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Journal ArticleDOI
Inflammation markers and risk factors for recurrence in 35 patients with a posttraumatic chronic subdural hematoma: a prospective study.
Alessandro Frati,Maurizio Salvati,Fabrizio Mainiero,Flora Ippoliti,Giovanni Rocchi,Antonino Raco,Emanuela Caroli,Giampaolo Cantore,Roberto Delfini +8 more
TL;DR: High levels of inflammatory cytokines were significantly correlated with recurrence and layering CSDH; a prolonged postoperative antiinflammatory medicine given as prophylaxis may help prevent the recurrence of a CSDH.
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Radiation-induced gliomas: report of 10 cases and review of the literature
Maurizio Salvati,Alessandro Frati,Natale Russo,Emanuela Caroli,Filippo Maria Polli,Giuseppe Minniti,Roberto Delfini +6 more
TL;DR: Though rare, gliomas may represent a late complication of radiation treatment and should be scrupulously evaluated when deciding whether to employ this method for therapeutic purposes for relatively benign or congenital lesions (which generally affect young patients with a long life expectancy).
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Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma
Marco Tafani,Maura Di Vito,Alessandro Frati,Laura Pellegrini,Elena De Santis,Giovanni Sette,Adriana Eramo,Patrizio Sale,Emanuela Mari,Antonio Santoro,Antonino Raco,Maurizio Salvati,Ruggero De Maria,Matteo Antonio Russo +13 more
TL;DR: It is suggested that, as has been previously described for prostatic and mammary carcinoma, in human glioblastoma acquisition of a proinflammatory phenotype may be relevant for malignant progression.
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Comparison of minimally invasive surgery with standard open surgery for vertebral thoracic metastases causing acute myelopathy in patients with short- or mid-term life expectancy: surgical technique and early clinical results.
Massimo Miscusi,Filippo Maria Polli,Stefano Forcato,Luca Ricciardi,Alessandro Frati,Marco Cimatti,Luca De Martino,Alessandro Ramieri,Antonino Raco +8 more
TL;DR: Minimally invasive spine surgery (MISS) is as safe and effective for spinal cord decompression and spine fixation as traditional surgery, and it also reduces the impact of surgery in critical patients.
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Diffuse Axonal Injury and Oxidative Stress: A Comprehensive Review.
Alessandro Frati,Daniela Cerretani,Anna Ida Fiaschi,Paola Frati,Vittorio Gatto,Raffaele La Russa,Alessandro Pesce,Enrica Pinchi,Alessandro Santurro,Flavia Fraschetti,Vittorio Fineschi +10 more
TL;DR: Following TBI, axonal degeneration has been identified as a progressive process that starts with disrupted axonal transport causing axonal swelling, followed by secondary axonal disconnection and Wallerian degeneration, and studies support the role of an altered axonal calcium homeostasis as a mechanism in the secondary damage of axon, and suggest that calcium channel blocker can alleviate the secondaryDamage.