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Alex M. Kreger
Publications - 4
Citations - 317
Alex M. Kreger is an academic researcher. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 1, co-authored 1 publications receiving 234 citations.
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Journal ArticleDOI
Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells
Diego V. Bohórquez,Rafiq A. Shahid,Alan Erdmann,Alex M. Kreger,Yu Wang,Nicole Calakos,Fan Wang,Rodger A. Liddle +7 more
TL;DR: It is determined that neuropods provide a direct connection between enteroendocrine cells and neurons innervating the small intestine and colon, and this neuroepithelial circuit can serve as both a sensory conduit for food and gut microbes to interact with the nervous system and a portal for viruses to enter the enteric and central nervous systems.
Journal ArticleDOI
Chemical pancreatectomy in non-human primates ablates the acini and ducts and enhances beta-cell function
Ranjeet Kalsi,Alex M. Kreger,Mohamed A. Saleh,Shiho Yoshida,Kartikeya Kumar Sharma,Joseph Fusco,Jami L. Saloman,Ting Zhang,Madison Thomas,Anuradha Sehrawat,Yan Wang,Jason Reif,J. R. Frank Mills,Sarah Raad,Buğra Zengin,Ana Gomez,Aatur D. Singhi,Sameh Tadros,Adam Slivka,Farzad Esni,Krishna Prasadan,George K. Gittes +21 more
TL;DR: In this paper , the feasibility of a chemical pancreatectomy in NHPs was evaluated using serial computed tomography (CT) scans of the abdomen and pelvis, analyzed dorsal root ganglia, measured serum enzymes, and performed histological and ultrastructural assessments and pancreatic endocrine function assays.
Journal ArticleDOI
Intra-amniotic sildenafil administration in rabbits: Safety, pharmacokinetics, organ distribution and histologic evaluation.
Shiho Yoshida,Alex M. Kreger,Imam H. Shaik,Raymond E. West,Raman Venkataramanan,George K. Gittes +5 more
TL;DR: In this article , the authors evaluated the pharmacokinetics of sildenafil after intra-amniotic (IA) administration in pregnant rabbits and found that the IA-sildenabolition of the drug significantly improved pulmonary hypertension in CDH patients.
Posted ContentDOI
Chemical pancreatectomy in non-human primates ablates the acini and ducts and enhances beta-cell function
Ranjeet Kalsi,Alex M. Kreger,Mohamed A. Saleh,Shiho Yoshida,Kartikeya Kumar Sharma,Joseph Fusco,Jami L. Saloman,Ting Zhang,Madison Thomas,Anuradha Sehrawat,Yan Wang,Jason Reif,J. R. Frank Mills,Sarah Raad,Buğra Zengin,Ana Gomez,Aatur D. Singhi,Sameh Tadros,Adam Slivka,Farzad Esni,Krishna Prasadan,George K. Gittes +21 more
TL;DR: In this paper , the feasibility of a chemical pancreatectomy in NHPs was evaluated using serial computed tomography (CT) scans of the abdomen and pelvis, analyzed dorsal root ganglia, measured serum enzymes, and performed histological and ultrastructural assessments and pancreatic endocrine function assays.