A
Alexander de Crespigny
Researcher at Stanford University
Publications - 22
Citations - 1867
Alexander de Crespigny is an academic researcher from Stanford University. The author has contributed to research in topics: Magnetic resonance imaging & Cortical spreading depression. The author has an hindex of 18, co-authored 22 publications receiving 1830 citations. Previous affiliations of Alexander de Crespigny include University of California, San Francisco & Harvard University.
Papers
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Journal ArticleDOI
Compromised white matter tract integrity in schizophrenia inferred from diffusion tensor imaging.
Kelvin O. Lim,Kelvin O. Lim,Maj Hedehus,Michael E. Moseley,Alexander de Crespigny,Edith V. Sullivan,Adolf Pfefferbaum,Adolf Pfefferbaum +7 more
TL;DR: Despite the small sample size, diffusion tensor imaging was powerful enough to yield significant group differences, indicating widespread alteration in brain white matter integrity but not necessarily white matter volume in schizophrenia.
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Longitudinal magnetic resonance imaging study of perfusion and diffusion in stroke: Evolution of lesion volume and correlation with clinical outcome
Christian Beaulieu,Alexander de Crespigny,David C. Tong,Michael E. Moseley,Gregory W. Albers,Michael P. Marks +5 more
TL;DR: Overall, lesion growth appeared to depend on the degree of mismatch between diffusion and perfusion at the initial scan, and DWI and PWI can provide an early measure of metabolic and hemodynamic insufficiency, and thus can improve the understanding of the evolution and outcome after acute ischemic stroke.
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Experimental Cerebral Venous Thrombosis: Evaluation Using Magnetic Resonance Imaging:
TL;DR: Experimental CVT is characterized by early cytotoxic edema closely followed by vasogenic edema, which encourages the use of cytoprotective drugs in addition to anticoagulant or thrombolytic therapy.
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MR Detection of Cortical Spreading Depression Immediately After Focal Ischemia in the Rat
TL;DR: Serial MR diffusion weighted imaging can detect the earliest dynamic, reversible ADC changes in the ischemic tissue and the speed of propagation of the decreasing ADC wave, the waveform characteristics, and the occurrence in moderately perturbated tissue are compatible with cortical spreading depression.
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Recovery of Apparent Diffusion Coefficient After Ischemia-Induced Spreading Depression Relates to Cerebral Perfusion Gradient
TL;DR: The variation in the recovery time of transient ADC decreases in the ischemic periphery reflects the gradient of the tissue perfusion.