A
Alexander Gural
Researcher at Hebrew University of Jerusalem
Publications - 41
Citations - 543
Alexander Gural is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 33 publications receiving 405 citations. Previous affiliations of Alexander Gural include Hadassah Medical Center.
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Journal ArticleDOI
Daratumumab resistance is frequent in advanced-stage multiple myeloma patients irrespective of CD38 expression and is related to dismal prognosis.
Marjorie Pick,Vladimir Vainstein,Neta Goldschmidt,David Lavie,Diana Libster,Alexander Gural,Sigal Grisariu,Batia Avni,Dina Ben Yehuda,Moshe E. Gatt +9 more
TL;DR: A single center “real‐world” series of multiple myeloma and amyloidosis patients treated with daratumumab is reported, indicating a promising new antimyeloma agent.
Journal ArticleDOI
Storage-induced damage to red blood cell mechanical properties can be only partially reversed by rejuvenation.
TL;DR: The findings of the present and preceding studies suggest that different St-RBC properties are differentially reversed by RJ, implying that some of the changes occur during storage and are irreversible.
Journal ArticleDOI
Age related microsatellite instability in T cells from healthy individuals.
Svetlana Krichevsky,Graham Pawelec,Alexander Gural,Rita B. Effros,Amiela Globerson,Dina Ben Yehuda,Arie Ben Yehuda +6 more
TL;DR: It is demonstrated that as CD8 lymphocytes from aged individuals, undergo repeated population doublings (PDs) in culture, they develop MSI, and CD4 clones that also undergo repeated PDs in culture develop significant MSI as well.
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A new point-of-care method for monitoring anti-platelet therapy: application of the cone and plate(let) analyzer.
Galia Spectre,Alexander Brill,Alexander Gural,Boris Shenkman,Natalia Touretsky,Elinor Mosseri,Naphtali Savion,David Varon +7 more
TL;DR: Themodified CPA test is a useful tool to evaluate the efficacy of anti-platelet therapy and a good correlation was observed between the modified CPA and aggregometry.
Journal ArticleDOI
Clinical considerations and key issues in the management of patients with Erdheim-Chester Disease: a seven case series
Roei D Mazor,Roei D Mazor,Mirra Manevich-Mazor,Anat Kesler,Orna Aizenstein,Iris Eshed,Ronald Jaffe,Yakov Pessach,Ilan Goldberg,Eli Sprecher,Iris Yaish,Alexander Gural,Chezi Ganzel,Yehuda Shoenfeld +13 more
TL;DR: ECD is a complex, multi-systemic, clonal entity coalescing both neoplastic and inflammatory elements and strongly dependent on impaired RAS/RAF/MEK/ERK signaling.