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Alexander V. Fonin
Researcher at Russian Academy of Sciences
Publications - 42
Citations - 632
Alexander V. Fonin is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 9, co-authored 31 publications receiving 394 citations. Previous affiliations of Alexander V. Fonin include Saint Petersburg State Polytechnic University & Moscow Institute of Physics and Technology.
Papers
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Journal ArticleDOI
Fluorescence of dyes in solutions with high absorbance. Inner filter effect correction.
TL;DR: It is shown that if dye molecules do not interact with each other and there is no reabsorption, then the dependence of experimentally detected total fluorescence intensity of the dye on its absorbance coincides with the calculated dependence and the correction factor for eliminating the primary inner filter effect can be calculated on the basis of solution absorbance.
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Stochasticity of Biological Soft Matter: Emerging Concepts in Intrinsically Disordered Proteins and Biological Phase Separation.
Konstantin K. Turoverov,Konstantin K. Turoverov,Irina M. Kuznetsova,Alexander V. Fonin,April L. Darling,Boris Y. Zaslavsky,Vladimir N. Uversky +6 more
TL;DR: Intrinsically disordered proteins (IDPs) and membrane-less organelles are key examples of this new outlook and may represent a critical foundation of life, defining its complexity and the evolution of living things.
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Intrinsically disordered proteins in crowded milieu: when chaos prevails within the cellular gumbo.
Alexander V. Fonin,April L. Darling,Irina M. Kuznetsova,Konstantin K. Turoverov,Konstantin K. Turoverov,Vladimir N. Uversky +5 more
TL;DR: This review represents a systematic analysis of the available literature data on the behaviour of IDPs/IDPRs in crowded environment and indicates that, based on their response to the presence of crowders, IDPs or intrinsically disordered protein regions can be grouped into three major categories, foldable, non-foldable, and unfoldable.
Journal ArticleDOI
Multi-functionality of proteins involved in GPCR and G protein signaling: making sense of structure–function continuum with intrinsic disorder-based proteoforms
Alexander V. Fonin,April L. Darling,Irina M. Kuznetsova,Konstantin K. Turoverov,Konstantin K. Turoverov,Vladimir N. Uversky,Vladimir N. Uversky +6 more
TL;DR: The multifunctionality of GPCR–G protein system represents an illustrative example of the protein structure–function continuum, where structures of the involved proteins represent a complex mosaic of differently folded regions.
Journal ArticleDOI
Liquid–liquid phase separation as an organizing principle of intracellular space: overview of the evolution of the cell compartmentalization concept
Iuliia A. Antifeeva,Alexander V. Fonin,Anna S. Fefilova,Olesya V. Stepanenko,Olga I. Povarova,Sergey A. Silonov,Irina M. Kuznetsova,Vladimir N. Uversky,Konstantin K. Turoverov +8 more
TL;DR: It is emphasized here that the membrane-less organelles have to combine a certain resistance to the changes in their environment and, at the same time, show high sensitivity to the external signals, which ensures the normal functioning of the cell.