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Alexandre Barbosa Reis
Researcher at Universidade Federal de Ouro Preto
Publications - 149
Citations - 4847
Alexandre Barbosa Reis is an academic researcher from Universidade Federal de Ouro Preto. The author has contributed to research in topics: Visceral leishmaniasis & Leishmania infantum. The author has an hindex of 37, co-authored 132 publications receiving 4223 citations. Previous affiliations of Alexandre Barbosa Reis include Universidade Federal de Minas Gerais & National Council for Scientific and Technological Development.
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Journal ArticleDOI
Impact of canine control on the epidemiology of canine and human visceral leishmaniasis in Brazil.
Clarisa B. Palatnik-de-Sousa,W R dos Santos,João Carlos França-Silva,R. T. Da Costa,Alexandre Barbosa Reis,Marcos Palatnik,Wilson Mayrink,Odair Genaro +7 more
TL;DR: Although difficult and expensive, the public health dog control campaigns performed in Brazil reduced the incidence of ZVL and should be maintained since treatment of dogs is an unrealistic intervention, both because of its prohibitive cost and relatively poor effectiveness.
Journal ArticleDOI
Parasite density and impaired biochemical/hematological status are associated with severe clinical aspects of canine visceral leishmaniasis
Alexandre Barbosa Reis,Alexandre Barbosa Reis,Olindo Assis Martins-Filho,Andréa Teixeira-Carvalho,Maria das Graças Carvalho,Wilson Mayrink,João Carlos França-Silva,Rodolfo Cordeiro Giunchetti,Rodolfo Cordeiro Giunchetti,Odair Genaro,Rodrigo Correa-Oliveira +10 more
TL;DR: It is observed that the progression of the disease from asymptomatic to symptomatic clinical form was accompanied by intense parasitism in the bone marrow, which led to the impaired biochemical/hematological status observed.
Journal ArticleDOI
Systemic and compartmentalized immune response in canine visceral leishmaniasis.
Alexandre Barbosa Reis,Olindo Assis Martins-Filho,Andréa Teixeira-Carvalho,Andréa Teixeira-Carvalho,Rodolfo Cordeiro Giunchetti,Rodolfo Cordeiro Giunchetti,Cláudia Martins Carneiro,Wilson Mayrink,Washington Luiz Tafuri,Rodrigo Correa-Oliveira +9 more
TL;DR: The main results demonstrated that lower frequency of circulating B cells and monocytes are important markers of severe CVL, whereas increased levels of CD8+ lymphocytes appear to be the major phenotypic feature of asymptomatic disease.
Journal ArticleDOI
Isotype patterns of immunoglobulins: hallmarks for clinical status and tissue parasite density in Brazilian dogs naturally infected by Leishmania (Leishmania) chagasi.
Alexandre Barbosa Reis,Andréa Teixeira-Carvalho,Andréa Teixeira-Carvalho,André Macedo Vale,Marcos José Marques,Rodolfo Cordeiro Giunchetti,Wilson Mayrink,L. L. Guerra,Renata Aline de Andrade,Rodrigo Correa-Oliveira,Olindo Assis Martins-Filho +10 more
TL;DR: The association between clinical status, Ig profile and the tissue parasitism support a novel investigation on the impact of humoral immune response and susceptibility/resistance mechanism during ongoing CVL, and re-enforce the anti-Leishmania IgG but with IgA reactivity as the better marker for overall tissue Parasitism.
Journal ArticleDOI
Prevalence and Factors Associated with Leishmania infantum Infection of Dogs from an Urban Area of Brazil as Identified by Molecular Methods
Wendel Coura-Vital,Wendel Coura-Vital,Marcos José Marques,Vanja Maria Veloso,Bruno Mendes Roatt,Rodrigo Dian de Oliveira Aguiar-Soares,Levi Eduardo Soares Reis,Samuel Leôncio Braga,Maria Helena Franco Morais,Alexandre Barbosa Reis,Mariângela Carneiro +10 more
TL;DR: Socioeconomic variables, dog behavior and the knowledge of the owner regarding the vector were factors associated with canine visceral leishmaniasis (CVL), and a lack of previous serological examination for VL was also associated with L. infantum infection.