A
Alexandre Colmant
Researcher at Cliniques Universitaires Saint-Luc
Publications - 5
Citations - 65
Alexandre Colmant is an academic researcher from Cliniques Universitaires Saint-Luc. The author has contributed to research in topics: Mycobacterium chelonae & Mycobacterium abscessus. The author has an hindex of 3, co-authored 5 publications receiving 48 citations.
Papers
More filters
Journal ArticleDOI
Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by commercial assays.
Emmanuel André,Emmanuel André,Léonie Goeminne,Alexandre Colmant,Patrick Beckert,Stefan Niemann,Michel Delmée,Michel Delmée +7 more
TL;DR: It is proposed that the detection of the rpoB Ile491Phe rPOB mutation should complement commercial assays for the diagnosis of rifampicin-resistant M. tuberculosis in routine conditions, particularly in countries where this specific mutation is frequent.
Journal ArticleDOI
Comparison of the RGM medium and the mycobacterial growth indicator tube automated system for isolation of non-tuberculous mycobacteria from sputum samples of cystic fibrosis patients in Belgium
Anaïs Scohy,Sophie Gohy,Vanessa Mathys,Guillaume Sapriel,Laetitia Toussaint,Florian Bressant,Ali Zitouni,Marie-Noël Teylaert,Marie-Christine Vander Meeren,Alexandre Colmant,Anne Simon,Anne Simon,John D. Perry,Patrick Lebecque,Emmanuel André,Emmanuel André +15 more
TL;DR: RGM medium increases the proportion of interpretable results and the number of NTM cultured, and can replace current approaches for the screening of N TM among people with CF, taking into account the non-inferiority compared to conventional methods and ease of use of RGM medium.
Journal ArticleDOI
Laboratory diagnosis of nontuberculous mycobacteria in a Belgium Hospital
TL;DR: The species diversity of NTM found in the setting suggests the importance of the use of new modern methods for accurate identification of N TM at species level and in some case at subspecies level for the proper treatment and management of patients.
Journal ArticleDOI
Targeting bedaquiline mycobacterial efflux pump to potentially enhance therapy in Mycobacterium abscessus.
Anandi Martin,Yasmine Bouyakoub,Kate Soumillion,Eléonore Ngyuvula Mantu,Alexandre Colmant,Hector Rodriguez-Villalobos +5 more
TL;DR: The results obtained in this study confirm that bedaquiline MIC decreased in the presence of EPIs verapamil and reserpine in clinical isolates of M. abscessus.
Journal ArticleDOI
Immune reconstitution inflammatory syndrome due to Mycobacterium genavense in an HIV-infected patient: Impact of rapid species identification by rpoB sequencing on clinical management
Emmanuel André,Emmanuel André,Leila Belkhir,Léonie Goeminne,Alexandre Colmant,Jean-Yves Sottiaux,Halil Yildiz,Jean Ruelle,Michel Delmée,Michel Delmée,Bernard Vandercam,Jean-Philippe Defour +11 more
TL;DR: The case of an HIV-1 positive patient presenting with severe NTM infection who benefited from a novel rapid diagnostic technique, based on the direct sequencing of the rpoB gene from smear-positive clinical samples, is reported.