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Alexandre Colmant

Researcher at Cliniques Universitaires Saint-Luc

Publications -  5
Citations -  65

Alexandre Colmant is an academic researcher from Cliniques Universitaires Saint-Luc. The author has contributed to research in topics: Mycobacterium chelonae & Mycobacterium abscessus. The author has an hindex of 3, co-authored 5 publications receiving 48 citations.

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Novel rapid PCR for the detection of Ile491Phe rpoB mutation of Mycobacterium tuberculosis, a rifampicin-resistance-conferring mutation undetected by commercial assays.

TL;DR: It is proposed that the detection of the rpoB Ile491Phe rPOB mutation should complement commercial assays for the diagnosis of rifampicin-resistant M. tuberculosis in routine conditions, particularly in countries where this specific mutation is frequent.
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Laboratory diagnosis of nontuberculous mycobacteria in a Belgium Hospital

TL;DR: The species diversity of NTM found in the setting suggests the importance of the use of new modern methods for accurate identification of N TM at species level and in some case at subspecies level for the proper treatment and management of patients.
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Targeting bedaquiline mycobacterial efflux pump to potentially enhance therapy in Mycobacterium abscessus.

TL;DR: The results obtained in this study confirm that bedaquiline MIC decreased in the presence of EPIs verapamil and reserpine in clinical isolates of M. abscessus.
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Immune reconstitution inflammatory syndrome due to Mycobacterium genavense in an HIV-infected patient: Impact of rapid species identification by rpoB sequencing on clinical management

TL;DR: The case of an HIV-1 positive patient presenting with severe NTM infection who benefited from a novel rapid diagnostic technique, based on the direct sequencing of the rpoB gene from smear-positive clinical samples, is reported.