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Alexandre Paiva
Researcher at Universidade Nova de Lisboa
Publications - 91
Citations - 4606
Alexandre Paiva is an academic researcher from Universidade Nova de Lisboa. The author has contributed to research in topics: Supercritical carbon dioxide & Solubility. The author has an hindex of 27, co-authored 91 publications receiving 3069 citations. Previous affiliations of Alexandre Paiva include University of Lisbon & Instituto Superior Técnico.
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Natural Deep Eutectic Solvents – Solvents for the 21st Century
Alexandre Paiva,Rita Craveiro,Ivo Manuel Ascensão Aroso,Marta Martins,Rui L. Reis,Ana Rita C. Duarte +5 more
TL;DR: Deep Eutectic Solvents (DES) as discussed by the authors are a class of solvents that can be defined as a mixture of two or more components, which at a particular composition present a high melting point depression becoming liquids at room temperature.
Journal ArticleDOI
Properties and thermal behavior of natural deep eutectic solvents
Rita Craveiro,Ivo Manuel Ascensão Aroso,V. Flammia,Tânia Carvalho,María Teresa Viciosa,Madalena Dionísio,Susana Barreiros,Rui L. Reis,Ana Rita C. Duarte,Alexandre Paiva +9 more
TL;DR: In this article, the properties of natural deep eutectic solvents (NADES) have been investigated at the molecular level, including their properties such as density, thermal behavior, conductivity and polarity.
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Natural deep eutectic solvents from choline chloride and betaine – Physicochemical properties
TL;DR: In this article, the preparation of natural deep eutectic solvents (NADESs) from cheap and readily available raw materials is reported, where mixtures of choline chloride (CC) or betaine (Bet) with 3 sugar molecules (glucose (Glu), xylose (Xyl) and sucrose (Suc)) and 2 carboxylic acids (citric (CA) and tartaric (Tart) acids).
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Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systems
Ivo Manuel Ascensão Aroso,João C. Silva,Francisca Mano,Ana S. Ferreira,Madalena Dionísio,Isabel de Sá-Nogueira,Susana Barreiros,Rui L. Reis,Alexandre Paiva,Ana Rita C. Duarte +9 more
TL;DR: The results show that all the THEDESs retain the antibacterial activity of the API, highlighting the great potential of THEDes as dissolution enhancers in the development of novel and more effective drug delivery systems.
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A comparison between pure active pharmaceutical ingredients and therapeutic deep eutectic solvents: Solubility and permeability studies
Ana Rita C. Duarte,Ana S. Ferreira,Susana Barreiros,Eurico J. Cabrita,Rui L. Reis,Alexandre Paiva +5 more
TL;DR: The efficiency of THEDES as a new formulation for the enhancement of the bioavailability of APIs by changing the physical state of the molecules from a solid dosage to a liquid system is demonstrated.