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Alexandros Ardavanis

Researcher at Yahoo!

Publications -  145
Citations -  2937

Alexandros Ardavanis is an academic researcher from Yahoo!. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 27, co-authored 130 publications receiving 2521 citations.

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Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patients.

TL;DR: MMP-9 status was compared with the concentration of cytosolic Cathepsin-D and with other established prognostic factors, in terms of disease free survival and overall survival and it is suggested that M MP-9 may be an independent favourable prognostic factor in node-negative breast cancer patients.
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A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer

TL;DR: In conclusion, repetitive infusions of allogeneic, in vitro activated and expanded with IL-15/HC NK cells, in combination with chemotherapy are safe and potentially clinically effective.
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The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias

TL;DR: Current knowledge on the role of BCL2 apoptosis regulator proteins in acute and chronic leukemias is described to lead to the design of new therapies which may improve patients' survival.
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Vinorelbine Plus Cisplatin Versus Docetaxel Plus Gemcitabine in Advanced Non-Small-Cell Lung Cancer: A Phase III Randomized Trial

TL;DR: Although the two regimens produced comparable overall survival, the DG regimen had a better toxicity profile and could be used in the first-line setting of advanced NSCLC, especially for patients who cannot tolerate cisplatin.
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CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients.

TL;DR: Treg cell frequency does not directly correlate with clinical stage in breast cancer, as stage III and IV HER+ and HER− patients exhibit significantly different Treg profiles.