Alexei Valerievich Yumashev

TL;DR: In this paper, the authors discuss the CAR signaling and efficacy T in solid tumors and evaluate the most significant barriers in this process and describe the most novel therapeutic methods aiming to the acquirement of the promising therapeutic outcome in non-hematologic malignancies.

TL;DR: In this paper, the authors explored the impact of the quality and volume of energy consumption of the population on the human development index using a sample of a number of countries as an example, and found that the size and rating of the HDI are influenced by such factors as urbanization growth, gross domestic product (GDP), gross national income (GNI) per capita, the share of clean energy consumption by the population and business in total energy consumption, the level of socioeconomic development, and R&D expenses.

TL;DR: In this article, mesenchymal stem/stromal cells (MSCs) exosomes are used to convey functional molecules such as long non-coding RNAs (lncRNAs) and micro-RNAs (miRNAs), proteins (e.g., chemokine and cytokine), and lipids from MSCs to target cells.

TL;DR: CAR-natural killer (CAR) cells combine the targeted specificity of antigens with the subsequent intracellular signaling ability of the receptors to increase their anti-cancer functions as discussed by the authors.