A
Alexey Schramko
Researcher at University of Helsinki
Publications - 39
Citations - 761
Alexey Schramko is an academic researcher from University of Helsinki. The author has contributed to research in topics: Thromboelastometry & Cardiopulmonary bypass. The author has an hindex of 14, co-authored 38 publications receiving 628 citations. Previous affiliations of Alexey Schramko include Helsinki University Central Hospital.
Papers
More filters
Journal ArticleDOI
Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy
Niels Rahe-Meyer,Jerrold H. Levy,C D Mazer,Alexey Schramko,Andrew A. Klein,Radim Brát,Yutaka Okita,Yuichi Ueda,Dirk S. Schmidt,R. Ranganath,Ravi Gill +10 more
TL;DR: Human fibrinogen concentrate was associated with increased allogeneic blood product transfusion, an unexpected finding contrary to previous studies, and may not be effective in this setting when administered according to 5-minute bleeding mass.
Journal ArticleDOI
Rapidly degradable hydroxyethyl starch solutions impair blood coagulation after cardiac surgery: a prospective randomized trial
TL;DR: It is concluded that a short-time infusion of rapidly degradable HES solutions after cardiac surgery produces impairment in fibrin formation and clot strength in thromboelastometry tracings.
Journal ArticleDOI
Hydroxyethylstarch and gelatin solutions impair blood coagulation after cardiac surgery: a prospective randomized trial
Alexey Schramko,Raili Suojaranta-Ylinen,Anne Kuitunen,Peter Raivio,Sinikka Kukkonen,Tomi T. Niemi +5 more
TL;DR: Even a small dose of HES 130/0.4 or gelatin impaired clot strength after cardiac surgery in a dose-dependent fashion, but neither colloid increased blood loss.
Journal ArticleDOI
Role of fibrinogen-, factor VIII- and XIII-mediated clot propagation in gelatin haemodilution.
TL;DR: The purpose of this study was to evaluate the capacity of single coagulation factors to reverse gelatin‐promoted whole‐blood coagulating disorders in vitro.
Journal ArticleDOI
Haemodynamics and acid-base equilibrium after cardiac surgery: comparison of rapidly degradable hydroxyethyl starch solutions and albumin.
TL;DR: The effect of albumin on cardiac performance is inferior than that of HES130 or HES200 in early postoperative phase after cardiac surgery in a prospective, randomized, open-label study.