A
Ali Asgar S. Bhagat
Researcher at National University of Singapore
Publications - 83
Citations - 7661
Ali Asgar S. Bhagat is an academic researcher from National University of Singapore. The author has contributed to research in topics: Circulating tumor cell & Microchannel. The author has an hindex of 30, co-authored 79 publications receiving 6704 citations. Previous affiliations of Ali Asgar S. Bhagat include Massachusetts Institute of Technology & Singapore–MIT alliance.
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Journal ArticleDOI
Isolation and retrieval of circulating tumor cells using centrifugal forces
Han Wei Hou,Majid Ebrahimi Warkiani,Bee Luan Khoo,Zi Rui Li,Ross A. Soo,Ross A. Soo,Daniel Shao-Weng Tan,Wan-Teck Lim,Jongyoon Han,Jongyoon Han,Ali Asgar S. Bhagat,Chwee Teck Lim,Chwee Teck Lim +12 more
TL;DR: The spiral biochip identifies and addresses key challenges of the next generation CTCs isolation assay including antibody independent isolation, high sensitivity and throughput (3 mL/hr); and single-step retrieval of viable C TCs.
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Inertial microfluidics for continuous particle separation in spiral microchannels
TL;DR: A spiral lab-on-a-chip (LOC) for size-dependent focusing of particles at distinct equilibrium positions across the microchannel cross-section from a multi-particle mixture is demonstrated for the first time.
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Continuous particle separation in spiral microchannels using dean flows and differential migration
TL;DR: A passive microfluidic device with spiral microchannel geometry for complete separation of particles that takes advantage of the dual role of Dean forces for focusing larger particles in a single equilibrium position and transposing the smaller particles from the inner half to the outer half of the microchannel cross-section.
Journal ArticleDOI
Microfluidics for cell separation.
Ali Asgar S. Bhagat,Hansen Bow,Han Wei Hou,Han Wei Hou,Swee Jin Tan,Jongyoon Han,Jongyoon Han,Chwee Teck Lim,Chwee Teck Lim +8 more
TL;DR: This review describes the current state-of-the-art in microfluidics-based cell separation techniques, and common separation metrics, including separation markers, resolution, efficiency, and throughput, of these techniques are discussed.
Journal ArticleDOI
Slanted spiral microfluidics for the ultra-fast, label-free isolation of circulating tumor cells
Majid Ebrahimi Warkiani,Guofeng Guan,Guofeng Guan,Khoo Bee Luan,Wong Cheng Lee,Ali Asgar S. Bhagat,Parthiv Kant Chaudhuri,Daniel Shao-Weng Tan,Wan-Teck Lim,Soo Chin Lee,Peter C. Y. Chen,Peter C. Y. Chen,Chwee Teck Lim,Jongyoon Han,Jongyoon Han +14 more
TL;DR: This work reports on a novel spiral microfluidic device with a trapezoidal cross-section for ultra-fast, label-free enrichment of CTCs from clinically relevant blood volumes, using the inherent Dean vortex flows present in curvilinear microchannels under continuous flow.