Alice Pau

TL;DR: Monitoring for development of Kaposi’s sarcoma and alternative treatment may be beneficial for patients with IRIS, especially in the presence of preexisting co-infection with Kaposi's Sarcoma–associated herpesvirus.

TL;DR: CC-11050 was well tolerated in PLWH, without affecting CD4 counts or plasma viremia, and led to a decrease in NK cells and plasma IL-8 level after 12-weeks of administration.

TL;DR: The finding that T97A-containing HIV emerged from a large replicating population from only a few viral lineages and persisted for months after discontinuing dolutegravir, has important implications as doluteGravir is rolled out worldwide.

TL;DR: In this paper, the authors examined the association between corticosteroids and bone turnover markers in severely lymphopenic HIV-infected patients initiating ART and found that corticostosteroids significantly reduced bone resorption and decreased bone mineral density.

TL;DR: The emergence of IRIS appears to be very common in people with HIV and disseminated histoplasmosis but the underlying trigger may be histoplasma, other co-infections or both.