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Alicja Grudowska
Researcher at Gdańsk Medical University
Publications - 4
Citations - 119
Alicja Grudowska is an academic researcher from Gdańsk Medical University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 3, co-authored 4 publications receiving 103 citations.
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Journal ArticleDOI
CD151 in cancer progression and metastasis: a complex scenario
TL;DR: Results of clinical analyses of CD151 expression in different types of cancer and a large number of in vivo models demonstrate its impact on tumour growth and invasion and implicate CD151 as a valuable diagnostic and prognostic marker as well as a potential target for anti-cancer therapy.
Journal ArticleDOI
Phosphorylation of RSK2 at Tyr529 by FGFR2-p38 enhances human mammary epithelial cells migration.
Dominika Czaplinska,Lukasz Turczyk,Alicja Grudowska,Magdalena Mieszkowska,Andrea D. Lipińska,Andrzej C. Skladanowski,Anna J. Zaczek,Hanna M. Romanska,Rafal Sadej +8 more
TL;DR: A new FGF2/FGFR2-p38-RSK2 pathway is identified, which may play a significant role in the pathogenesis and progression of breast cancer and, hence, may present a novel therapeutic target in the treatment of FG FR2-expressing tumours.
Journal ArticleDOI
Tetraspanin CD151 mediates communication between PC3 prostate cancer cells and osteoblasts.
Alicja Grudowska,Dominika Czaplinska,Wojciech Połom,Marcin Matuszewski,Rafał Sądej,Andrzej C. Skladanowski +5 more
TL;DR: Data revealed that knockdown of CD151 abolished activation of pro-migratory/pro-survival kinases triggered by osteoblasts, along with expression of matrix metalloproteinase-13, which suggests that CD151 participates in communication between PC3 cells and bone microenvironment and the process can be considered as a significant step of PCa progression and metastasis.