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Alicja Wawrzynow
Researcher at University of Maryland, Baltimore
Publications - 4
Citations - 150
Alicja Wawrzynow is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Endoplasmic reticulum & Casein kinase 2. The author has an hindex of 4, co-authored 4 publications receiving 147 citations.
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Journal ArticleDOI
Sarcolipin, the "proteolipid" of skeletal muscle sarcoplasmic reticulum, is a unique, amphipathic, 31-residue peptide.
Alicja Wawrzynow,Janet L. Theibert,C. M. Murphy,Istvan Jona,Anthony Martonosi,John H. Collins +5 more
TL;DR: The name sarcolipin is proposed for this small protein, to signify its lipid-like solubility and association with the sarcoplasmic reticulum of rabbit skeletal muscle, and the molecular weight calculated from the sequence agrees with that measured by fast atom bombardment mass spectrometry, showing that sarcolippin contains no attached fatty acyl or other prosthetic groups.
Journal ArticleDOI
Identification of the site phosphorylated by casein kinase II in smooth muscle caldesmon
Alicja Wawrzynow,John H. Collins,Natalia V. Bogatcheva,Alexander V. Vorotnikov,Nikolai B. Gusev +4 more
TL;DR: Ser73 is the main site phosphorylated by casein kinase II in avian gizzard caldesmon, and is presumed to be phosphorserine.
Journal ArticleDOI
Chemical modification of the Ca2+-ATPase of rabbit skeletal muscle sarcoplasmic reticulum: identification of sites labeled with aryl isothiocyanates and thiol-directed conformational probes
Alicja Wawrzynow,John H. Collins +1 more
TL;DR: The Ca(2+)-ATPase labeling sites for three thiol-directed spectroscopic probes are investigated and the results do not support the widely held assumptions that Cys-344 andCys-364 are the most reactive residues with maleimide-based reagents, while Cys -670 and CYS-674 react most rapidly with iodoacetamide derivatives.
Journal ArticleDOI
An iodoacetamide spin-label selectively labels a cysteine side chain in an occluded site on the sarcoplasmic reticulum calcium-ATPase
TL;DR: Sarcoplasmic reticulum vesicles were labeled with iodoacetamide spin-label under conditions where time courses of the reaction predicted that one amino acid residue would be preferentially labeled, and the ISL reaction was found to be more selective than 6-(iodoacetamido)fluorescein (IAF).