An overview of the structure and magnetism of spinel ferrite nanoparticles and their synthesis in microemulsions

Recent advances in nanoparticle synthesis with reversed micelles.

The first part of this review looks at the fundamental properties of hydroxyapatite (HAP), the basic mineral constituent of mammalian hard tissues, including the physicochemical features that govern its formation by precipitation. A special emphasis is placed on the analysis of qualities of different methods of synthesis and of the phase transformations intrinsic to the formation of HAP following precipitation from aqueous solutions. This serves as an introduction to the second part and the main subject of this review, which relates to the discourse regarding the prospects of fabrication of ultrafine, nanosized particles based on calcium phosphate carriers with various therapeutic and/or diagnostic agents coated on and/or encapsulated within the particles. It is said that the particles could be either surface-functionalized with amphiphiles, peptides, proteins, or nucleic acids or injected with therapeutic agents, magnetic ions, or fluorescent molecules. Depending on the additive, they could be subsequently used for a variety of applications, including the controlled delivery and release of therapeutic agents (extracellularly or intracellularly), magnetic resonance imaging and hyperthermia therapy, cell separation, blood detoxification, peptide or oligonucleotide chromatography and ultrasensitive detection of biomolecules, and in vivo and in vitro gene transfection. Calcium phosphate nanoparticles as carriers of therapeutic agents that would enable a controlled drug release to treat a given bone infection and at the same be resorbed in the body so as to regenerate hard tissue lost to disease are emphasized hereby as one of the potentially attractive smart materials for the modern medicine.

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Nanosized hydroxyapatite and other calcium phosphates: chemistry of formation and application as drug and gene delivery agents.

Synthesis and surface functionalization of silica nanoparticles for nanomedicine.

Recent developments and trends of sol-gel auto-combustion method for spinel ferrite nanomaterial synthesis are briefly discussed and critically analyzed. The analysis of various parameters of reaction which could be used for better understanding of synthesis process and control of microstructure and property of spinel ferrite nanopowder products was the main objective of this review article. Special attention was paid to variety of particle size and phase purity. For these purposes the correlation between complexant, oxygen balance and combustion process chemical additives, as well as heating mechanism and atmosphere, was established. These results are relevant from standpoints of both application and processing of ferrites.

Sol-gel auto-combustion synthesis of spinel-type ferrite nanomaterials

The synthesis of spinel–ferrite nanoparticles using precipitation in microemulsions for ferrofluid applications

Nanocrystalline MnZn-ferrite particles with different morphology were prepared from single water-in-oil microemulsion consisting of n-hexanol as an oil phase, surfactant CTAB and an aqueous solution of mixed metal sulfates. A sodium hydroxide solution was used as the precipitating agent and a hydrogen peroxide as the oxidizing reagent. The synthesized materials were characterized using an X-ray diffraction (XRD), transmission electron microscope (TEM), BET surface analyzer and magnetometry.

Preparation of MnZn-ferrite with microemulsion technique

Silica-coated lanthanum–strontium manganite particles with La0.76Sr0.24MnO3+δ stoichiometric formula, exhibiting Curie temperature at ∼40°C, were prepared by using a traditional solid-state method of synthesis of magnetic ceramic particles, followed by milling and a low-temperature coating procedure in an aqueous alcoholic alkali medium. The properties of the obtained material establish it as a potential candidate for self-regulated power-absorbing and temperature-controlling materials in hyperthermia treatments. Moreover, core-comprising LaSr–manganites with different stoichiometries, ranging from La0.5Sr0.5MnO3+δ to LaMnO3+δ, were synthesized, with magnetic and structural properties examined thereof. Herein reported findings can potentially be used in the preparation of silica-coated magnetic particles with designable Curie temperature, offering a wide range of possibilities of adapting the material to practical instrumental setups in drug delivery and hyperthermia treatments.

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Preparation of Silica-Coated Lanthanum-Strontium Manganite Particles with Designable Curie Point, for Application in Hyperthermia Treatments

https://digitalcommons.chapman.edu/cgi/viewcontent.cgi?article=1332&context=pharmacy_articles

Aljoša Košak

Papers

The synthesis of spinel–ferrite nanoparticles using precipitation in microemulsions for ferrofluid applications

Preparation of MnZn-ferrite with microemulsion technique

Preparation of Silica-Coated Lanthanum-Strontium Manganite Particles with Designable Curie Point, for Application in Hyperthermia Treatments

Silica-coated lanthanum–strontium manganites for hyperthermia treatments

In situ synthesis of magnetic MnZn-ferrite nanoparticles using reverse microemulsions