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Aly A. Abdelbary
Researcher at Cairo University
Publications - 31
Citations - 1324
Aly A. Abdelbary is an academic researcher from Cairo University. The author has contributed to research in topics: Transdermal & Niosome. The author has an hindex of 17, co-authored 28 publications receiving 885 citations. Previous affiliations of Aly A. Abdelbary include University of the Pacific (United States) & Egyptian Atomic Energy Authority.
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Journal ArticleDOI
Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study.
TL;DR: The results showed that targeted MTX delivery might be achieved using topically applied niosomes for enhanced treatment of psoriasis.
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Investigating the potential of employing bilosomes as a novel vesicular carrier for transdermal delivery of tenoxicam.
TL;DR: Both, ex vivo permeation and in vivo skin deposition studies confirmed the superiority of bilosomes over drug solution in delivering TX transdermally and in vitro histopathological study proved the safety of topically applied bilosome.
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Sucrose stearate-based proniosome-derived niosomes for the nebulisable delivery of cromolyn sodium.
TL;DR: A novel approach was developed for the preparation of controlled release proniosome-derived niosomes, using sucrose stearates as non-ionic biocompatible surfactants for the nebulisable delivery of cromolyn sodium, and offers an alternative approach to minimize the problems associated with conventional niosome like degradation, sedimentation, aggregation and fusion.
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Fabrication of novel ultradeformable bilosomes for enhanced ocular delivery of terconazole: In vitro characterization, ex vivo permeation and in vivo safety assessment.
TL;DR: In vivo ocular tolerance and histopathological studies conducted using male albino rabbits proved the safety of the fabricated UBs after topical ocular application and confirmed that UBs could be promising for ocular drug delivery.
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Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers
TL;DR: The saturation solubility, in vitro dissolution rate and relative bioavailability of DCN were significantly increased after nanocrystallization, and the selected formula (F12) showed a higher bioavailability compared to the reference market product with relative bio availability of 131.4%.