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Amanda C. Jones
Researcher at California Institute of Technology
Publications - 29
Citations - 1045
Amanda C. Jones is an academic researcher from California Institute of Technology. The author has contributed to research in topics: Reactivity (chemistry) & Catalysis. The author has an hindex of 14, co-authored 29 publications receiving 933 citations. Previous affiliations of Amanda C. Jones include University of Wisconsin-Madison & Wake Forest University.
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Reversible inhibitor of p97, DBeQ, impairs both ubiquitin-dependent and autophagic protein clearance pathways
Tsui-Fen Chou,Steve J. Brown,Dmitriy Minond,Brian E. Nordin,Kelin Li,Amanda C. Jones,Peter Chase,Patrick Porubsky,Brian M. Stoltz,Frank J. Schoenen,Matthew P. Patricelli,Peter Hodder,Hugh Rosen,Raymond J. Deshaies +13 more
TL;DR: N2,N4-Dibenzylquinazoline-2,4-diamine (DBeQ) was identified as a selective, potent, reversible, and ATP-competitive p97 inhibitor that blocks multiple processes that have been shown by RNAi to depend on p97, including degradation of ubiquitin fusion degradation and endoplasmic reticulum-associated degradation pathway reporters.
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Toward a Symphony of Reactivity: Cascades Involving Catalysis and Sigmatropic Rearrangements
TL;DR: This work will attempt to review an area of synthesis that has fascinated us and that the authors find extraordinarily beautiful, namely the combination of catalysis and sigmatropic rearrangements in consecutive and cascade sequences.
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Reactivity of individual organolithium aggregates: a RINMR study of n-butyllithium and 2-methoxy-6-(methoxymethyl)phenyllithium.
TL;DR: Measurements show that the difference in reactivity between the lower and higher aggregates of organolithium reagents can be many order of many order.
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A unique Au-Ag-Au triangular motif in a trimetallic halonium dication: silver incorporation in a gold(I) catalyst.
TL;DR: Preliminary studies support the presence of the mixed gold/silver structure in solution and revealed that the ωB97X-D functional gave a better fit to the experimental data compared with the PBE0 functional, which has previously failed to capture aurophilic interactions.