Amanda Hanora Lavan

TL;DR: Good clinical practice for detecting and predicting ADRs in vulnerable patients includes detailed documentation and regular review of prescribed and over-the-counter medications through standardized medication reconciliation.

TL;DR: STOPPFrail comprises 27 criteria relating to medications that are potentially inappropriate in frail older patients with limited life expectancy and may assist physicians in deprescribing medications in these patients.

TL;DR: This review examines the various ways of minimizing prescribing errors in multimorbid older people and published data support focused prescriber education in geriatric pharmacotherapy, routine application of STOPP/START criteria for potentially inappropriate prescribing, electronic prescribing, and close liaison between clinical pharmacists and physicians in relation to structured medication review and reconciliation.

TL;DR: In this paper, a pragmatic, multi-national, parallel arm prospective randomized open-label, blinded endpoint (PROBE) controlled trial enrolling patients at six European medical centres was conducted, where 1,537 older medical and surgical patients with multi-morbidity and polypharmacy on admission were randomized to SENATOR software-guided medication optimization plus standard care.

TL;DR: It is identified that ADRs caused or contributed to one in five hospital admissions of patients with cancer, and more than 21% of admissions to an oncology service are ADR-related.