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Amit Jain
Researcher at Johns Hopkins University
Publications - 245
Citations - 4748
Amit Jain is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Medicine & Retrospective cohort study. The author has an hindex of 29, co-authored 222 publications receiving 3163 citations. Previous affiliations of Amit Jain include Johns Hopkins University School of Medicine & University of California, Berkeley.
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Probing cellular mechanobiology in three-dimensional culture with collagen-agarose matrices
TL;DR: It is found that agarose increases the elasticity of 3D collagen ECMs over two orders of magnitude with modest effect on collagen fiber organization, and this results are consistent with a model in which Agarose shifts ECM dissipation of cell-induced stresses from non-affine deformation of individual collagen fibers to bulk-affines of a continuum network.
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Dislocation of a primary total hip arthroplasty is more common in patients with a lumbar spinal fusion.
Aaron J. Buckland,Aaron J. Buckland,V. Puvanesarajah,V. Puvanesarajah,Jonathan M. Vigdorchik,Ran Schwarzkopf,Amit Jain,Eric O. Klineberg,R. A. Hart,J. J. Callaghan,J. J. Callaghan,Hamid Hassanzadeh,Hamid Hassanzadeh +12 more
TL;DR: Patients with a previous history of lumbar spinal fusion have a significantly higher rate of dislocation of their THA than age‐ and gender‐matched patients without a lumbAR spinal fusion.
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Prostaglandin E2 mediates sensory nerve regulation of bone homeostasis
Hao Chen,Hao Chen,Bo Hu,Bo Hu,Xiao Lv,Shouan Zhu,Gehua Zhen,Mei Wan,Amit Jain,Bo Gao,Yu Chai,Mi Yang,Xiao Wang,Ruoxian Deng,Lei Wang,Yong Cao,Shuangfei Ni,Shen Liu,Wen Yuan,Huajiang Chen,Xinzhong Dong,Yun Guan,Huilin Yang,Xu Cao +23 more
TL;DR: Prostaglandin E2, secreted by osteoblasts, activates the EP4 receptor on sensory nerves, inhibiting sympathetic nerve activity and modulating bone formation in mice, showing that PGE2 mediates sensory nerve to control bone homeostasis and promote regeneration.
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Three-column osteotomies in the treatment of spinal deformity in adult patients 60 years old and older: outcome and complications
Hamid Hassanzadeh,Amit Jain,Mostafa H. El Dafrawy,Michael C. Ain,Addisu Mesfin,Richard L. Skolasky,Khaled M. Kebaish +6 more
TL;DR: In the elderly patient, PSO and VCR can achieve significant restoration of sagittal and coronal balance and significant improvement in quality of life and should be selectively used.
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SARS-CoV-2 Impact on Elective Orthopaedic Surgery: Implications for Post-Pandemic Recovery.
TL;DR: It will take 7, 12, and 16 months-in optimistic, ambivalent, and pessimistic scenarios, respectively-until the health-care system can perform 90% of the expected pre-pandemic forecasted volume of surgery.