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Amit M. Oza

Researcher at Princess Margaret Cancer Centre

Publications -  542
Citations -  25057

Amit M. Oza is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 65, co-authored 485 publications receiving 19164 citations. Previous affiliations of Amit M. Oza include University Health Network & Ontario Institute for Cancer Research.

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Bevacizumab (B) plus erlotinib (E) for patients (pts) with recurrent ovarian (OC) and fallopian tube (FT) cancer: Preliminary results of a multi-center phase II trial

TL;DR: The first stage of accrual is complete and further enrollment is on hold pending continued efficacy evaluation of BE in pts with recurrent OC, primary peritoneal, and FT cancer, and there appeared to be an increased rate of bowel perforation.
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Liarozole fumarate (R85246): in the treatment of ER negative, tamoxifen refractory or chemotherapy resistant postmenopausal metastatic breast cancer.

TL;DR: Three phase II studies were conducted to determine the efficacy and tolerability of liarozole fumarate, a retinoic acid metabolism blocking agent (RAMBA) and aromatase inhibitor and demonstrated dose-dependent anti-tumor effects in the rats, only partially overcome by coadministration of estradiol.
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Baseline clinical predictors of antitumor response to the PARP inhibitor olaparib in germline BRCA1/2 mutated patients with advanced ovarian cancer

TL;DR: PTPI may be used to refine the prediction of response to PARP inhibition based on the conventional categorization of platinum sensitivity, an international multicenter retrospective study on the basis of baseline clinical characteristics of patients with advanced BRCA1/2 mutation ovarian cancers.
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Evaluation of an intraperitoneal chemotherapy program implemented at the Princess Margaret Hospital for patients with epithelial ovarian carcinoma.

TL;DR: A prospective evaluation of an ambulatory intraperitoneal (IP) /intravenous (IV) chemotherapy regimen for women with epithelial ovarian carcinoma and found this regimen is convenient for patients and potentially more cost effective than other published IP cisplatin-based regimens.
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COVID-19 Testing in Patients with Cancer: Does One Size Fit All?

TL;DR: A comprehensive review of the available evidence regarding SARS-CoV-2 testing in asymptomatic cancer patients is performed, and the approach adopted at Princess Margaret Cancer Centre (Toronto, Canada) is described as a core component of COVID-19 control.