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Amit M. Oza

Researcher at Princess Margaret Cancer Centre

Publications -  542
Citations -  25057

Amit M. Oza is an academic researcher from Princess Margaret Cancer Centre. The author has contributed to research in topics: Ovarian cancer & Cancer. The author has an hindex of 65, co-authored 485 publications receiving 19164 citations. Previous affiliations of Amit M. Oza include University Health Network & Ontario Institute for Cancer Research.

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Molecular correlates (EGFR status) and plasma VEGF levels associated with a phase II study of bevacizumab plus erlotinib (BE) for patients with recurrent ovarian cancer (OC) and fallopian tube (FT) cancer

TL;DR: This work examined the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) factors for prognostic value in the setting of treatment with BE and found that these factors may correlate with poor prognosis.
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Final results of a phase I study of adjuvant chemoradiation for gastric adenocarcinoma with infusional 5-fluorouracil and bi-weekly cisplatin.

TL;DR: The maximum tolerated dose (MTD) of 2-weekly cisplatin, infusional 5-FU and concurrent conformal radiotherapy for resected gastric cancer was assessed in this phase I study.
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ENGOT-ov60/GOG-3052/RAMP 201: A phase 2 study of VS-6766 (RAF/MEK clamp) alone and in combination with defactinib (FAK inhibitor) in recurrent low-grade serous ovarian cancer (LGSOC).

TL;DR: In this proof-of-concept study, durable objective responses have been reported in recurrent LGSOC pts, including pts who have had a prior MEK inhibitor and the combination of VS-6766 + defactinib has received FDA Breakthrough Therapy Designation for recurrent L GSOC.