A
Amiya K. Hajra
Researcher at University of Michigan
Publications - 108
Citations - 5336
Amiya K. Hajra is an academic researcher from University of Michigan. The author has contributed to research in topics: Dihydroxyacetone phosphate & Peroxisome. The author has an hindex of 42, co-authored 108 publications receiving 5221 citations. Previous affiliations of Amiya K. Hajra include University of California, Los Angeles & Beaumont Hospital.
Papers
More filters
Journal ArticleDOI
Glycerolipid Biosynthesis in Peroxisomes via the Acyl Dihydroxyacetone Phosphate Pathway
Amiya K. Hajra,James Bishop +1 more
TL;DR: Acyl-DHAP was discovered as a rapidly labeled lipid that was formed in crude mitochondrial fraction from 3'Pi or y-32P[ATP].3 This rapid labeling was due to the enzymatic dephosphorylation and rephosphorelysis of endogenous acyl- DHAP present in the crude mitochondrial fractions.
Journal ArticleDOI
Phenotype of patients with peroxisomal disorders subdivided into sixteen complementation groups
Ann B. Moser,Magnhild Rasmussen,Sakkubai Naidu,Paul A. Watkins,Martina C. Mcguinness,Amiya K. Hajra,Grace L. Chen,Gerald V. Raymond,Angela Liu,Donald Gordon,Karen Garnaas,David S. Walton,Ola H. Skjeldal,Mary Anne Guggenheim,Laird G. Jackson,Ellen R. Elias,Hugo W. Moser +16 more
TL;DR: At least 16 complementation groups, and hence genotypes, are associated with clinical manifestations of disorders of peroxisome assembly, including the Zellweger syndrome, neonatal adrenoleukodystrophy, infantile Refsum disease, and rhizomelic chondrodysplasia punctata.
Journal ArticleDOI
Neonatal adrenoleukodystrophy: new cases, biochemical studies, and differentiation from Zellweger and related peroxisomal polydystrophy syndromes
Richard I. Kelley,N. S. Datta,W. B. Dobyns,Amiya K. Hajra,Ann B. Moser,M. J. Noetzel,Elaine H. Zackai,Hugo W. Moser +7 more
TL;DR: It is concluded that NALD and the ZS probably represent at least two different genetic defects.
Journal ArticleDOI
Subcellular localization of acyl coenzyme A: dihydroxyacetone phosphate acyltransferase in rat liver peroxisomes (microbodies).
TL;DR: It was concluded that dihydroxyacetone phosphate acyltransferase is primarily localized in rat liver peroxisomes (microbodies) and a portion of this reductase is also present in the microsomal fraction.
Journal ArticleDOI
Deficiency of enzymes catalyzing the biosynthesis of glycerol−ether lipids in Zellweger syndrome: a new category of metabolic disease involving the absence of peroxisomes
TL;DR: The results support prior studies emphasizing the role of peroxisomes and the acyl DHAP pathway in cellular ether lipid synthesis, establish Zellweger syndrome cells as valuable for elucidating peroxISomal functions, and provide prenatal and postnatal diagnostic assays as well as potential therapeutic strategies for Zell weger syndrome.