Vulnerable periods during the development of the nervous system are sensitive to environmental insults because they are dependent on the temporal and regional emergence of critical developmental processes (i.e., proliferation, migration, differentiation, synaptogenesis, myelination, and apoptosis). Evidence from numerous sources demonstrates that neural development extends from the embryonic period through adolescence. In general, the sequence of events is comparable among species, although the time scales are considerably different. Developmental exposure of animals or humans to numerous agents (e.g., X-ray irradiation, methylazoxymethanol, ethanol, lead, methyl mercury, or chlorpyrifos) demonstrates that interference with one or more of these developmental processes can lead to developmental neurotoxicity. Different behavioral domains (e.g., sensory, motor, and various cognitive functions) are subserved by different brain areas. Although there are important differences between the rodent and human brain, analogous structures can be identified. Moreover, the ontogeny of specific behaviors can be used to draw inferences regarding the maturation of specific brain structures or neural circuits in rodents and primates, including humans. Furthermore, various clinical disorders in humans (e.g., schizophrenia, dyslexia, epilepsy, and autism) may also be the result of interference with normal ontogeny of developmental processes in the nervous system. Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function. This concern is compounded by the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans.

Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.

Sexual Behavior in the Human Male

This article explains how alcohol makes social responses more extreme, enhances important self-evaluations, and relieves anxiety and depression, effects that underlie both the social destructiveness of alcohol and the reinforcing effects that make it an addictive substance. The theories are based on alcohol's impairment of perception and thought--the myopia it causes--rather than on the ability of alcohol's pharmacology to directly cause specific reactions or on expectations associated with alcohol's use. Three conclusions are offered (a) Alcohol makes social behaviors more extreme by blocking a form of response conflict. (b) The same process can inflate self-evaluations. (c) Alcohol myopia, in combination with distracting activity, can reliably reduce anxiety and depression in all drinkers by making it difficult to allocate attention to the thoughts that provoke these states. These theories are discussed in terms of their significance for the prevention and treatment of alcohol abuse.

https://psycnet.apa.org/journals/amp/45/8/921.pdf

Alcohol myopia. Its prized and dangerous effects.

Contemporary urge models assume that urges are necessary but not sufficient for the production of drug use in ongoing addicts, are responsible for the initiation of relapse in abstinent addicts, and can be indexed across 3 classes of behavior: verbal report, overt behavior, and somatovisceral response. A review of available data does not provide strong support for these assumptions. An alternative cognitive model of drug use and drug urges is proposed that hypothesizes that drug use in the addict is controlled by automatized action schemata. Urges are conceptualized as responses supported by nonautomatic cognitive processes activated in parallel with drug-use action schemata either in support of the schema or in support of attempts to block the execution of the schema. The implications of this model for the assessment of urge responding and drug-use behavior are presented.

A cognitive model of drug urges and drug-use behavior: role of automatic and nonautomatic processes.

It has been widely asserted that low self-esteem causes violence, but laboratory evidence is lacking, and some contrary observations have characterized aggressors as having favorable self-opinions. In 2 studies, both simple self-esteem and narcissism were measured, and then individual participants were given an opportunity to aggress against someone who had insulted them or praised them or against an innocent third person. Self-esteem proved irrelevant to aggression. The combination of narcissism and insult led to exceptionally high levels of aggression toward the source of the insult. Neither form of self-regard affected displaced aggression, which was low in general. These findings contradict the popular view that low self-esteem causes aggression and point instead toward threatened egotism as an important cause.

/pdf/threatened-egotism-narcissism-self-esteem-and-direct-and-4c42mc0dhd.pdf

Threatened egotism, narcissism, self-esteem, and direct and displaced aggression: Does self-love or self-hate lead to violence?

The most widely used measure of trait narcissism is the Narcissistic Personality Inventory (NPI), which can provide both total and subscale scores. However, with a length of 40 items, this measure may not be ideal in settings in which time or participant attention may limit the types of measures that can be administered. In response, Ames, Rose, and Anderson (2006) created the NPI-16, which provides a shorter, unidimensional measure of the construct. In the present research, we examine the reliability and validity of the NPI-16 in conjunction with a new short measure of narcissism, the NPI-13, which provides both a total score and 3 subscale scores (Leadership/Authority; Grandiose Exhibitionism; Entitlement/Exploitativeness). Across 2 studies, we demonstrate that both short measures manifest good convergent and discriminant validity and adequate overall reliability. The NPI-13 may be favored over the NPI-16 because it allows for the extraction of 3 subscales, consistent with the use of its parent measure.

/pdf/a-test-of-two-brief-measures-of-grandiose-narcissism-the-3pgzu28hh8.pdf

A test of two brief measures of grandiose narcissism: the narcissistic personality inventory-13 and the narcissistic personality inventory-16.

This study tested the construct validity (convergent and discriminant) of a competitive reaction-time aggression paradigm. Seventy-nine males completed three trait aggression questionnaires and then competed on a reaction-time task whereby they received and delivered shocks to a fictitious opponent. Results demonstrated strong positive relationships between shock intensity administered and the trait measures of overt aggression but not with the measures unrelated to overt aggression. Results are discussed with regard to their contribution to the construct validity of the aggression paradigm used in this study.

Construct validity of a competitive reaction‐time aggression paradigm

Effects of narcissistic entitlement and exploitativeness on human physical aggression

Given substantial interest in the traits conceived of as part of the Dark Triadpsychopathy, narcissism,and Machiavellianismassessment of these traits is of great importance. The Dirty Dozen (DD; Jonason& Webster, 2010) is a brief measure of the Dark Triad constructs that uses 4 items to assess each of theseconstructs. In the present study, the authors examined the adequacy of the DDs Psychopathy scale bycomparing it with established measures of psychopathy in a sample of undergraduates (Sample 1: N 789) and male prisoners (Sample 2: N 75). DDs Psychopathy subscale manifested significantcorrelations with established measures, but the correlations were smaller than those evinced by theexisting scales. The results also demonstrated that there is important variance related to interpersonalantagonism and disinhibition that is not assessed by the DD. The authors suggest that caution should beused in relying on the DD as a measure of psychopathy.Keywords: psychopathy, brief measures, construct validity, assessment

An examination of the Dirty Dozen measure of psychopathy: a cautionary tale about the costs of brief measures.

The authors assessed the biphasic effects of alcohol on human physical aggression. Sixty male social drinkers were assigned to 1 of 4 groups: alcohol ascending limb (AAL), alcohol descending limb (ADL), or 1 of 2 sober control groups. Aggression was assessed in the AAL and ADL groups at respective ascending or descending blood alcohol concentrations (BAC) of 0.08%. Each participant in the control groups was respectively yoked with a participant in either the AAL or the ADL group to control for the longer period of time needed to reach a BAC of 0.08% on the descending limb compared with the ascending limb (i.e., passage of time effect). The authors measured aggression using a modified version of the Taylor aggression paradigm (S. Taylor, 1967), in which electric shocks are received from and administered to a fictitious opponent during a competitive task. The AAL group was more aggressive than the ADL groups. There were no differences between the ADL group and the control groups, which suggests that alcohol does not appear to increase aggression on the descending limb. The control groups did not differ in aggression, thus ruling out a passage of time effect.

Amos Zeichner

Papers

A test of two brief measures of grandiose narcissism: the narcissistic personality inventory-13 and the narcissistic personality inventory-16.

Construct validity of a competitive reaction‐time aggression paradigm

Effects of narcissistic entitlement and exploitativeness on human physical aggression

An examination of the Dirty Dozen measure of psychopathy: a cautionary tale about the costs of brief measures.

The biphasic effects of alcohol on human physical aggression