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Amy K. Wagner

Researcher at University of Pittsburgh

Publications -  171
Citations -  6799

Amy K. Wagner is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Traumatic brain injury & Poison control. The author has an hindex of 44, co-authored 162 publications receiving 5853 citations. Previous affiliations of Amy K. Wagner include Boston Children's Hospital.

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Concussion in sports: postconcussive activity levels, symptoms, and neurocognitive performance.

TL;DR: Activity level after concussion affected symptoms and neurocognitive recovery, and athletes engaging in high levels of activity after concussion demonstrated worse neuroc cognitive performance.
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Persistent cognitive dysfunction after traumatic brain injury: A dopamine hypothesis

TL;DR: Clinical and experimental research examining DAergic therapies after TBI is discussed, which will in turn elucidate the importance of DA for cognitive function/dysfunction after TBO as well as highlight the areas that require further study.
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Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making.

TL;DR: Multifaceted cellular, biochemical, and molecular monitoring of proteins and lipids is logical as an adjunct to guiding therapies and improving outcomes in traumatic and ischemic brain injury and appears to be on the verge of a breakthrough with the use of these markers as diagnostic, prognostic, and monitoring adjuncts, in neurointensive care.
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IL‐1β associations with posttraumatic epilepsy development: A genetics and biomarker cohort study

TL;DR: It is hypothesized that TBI‐induced inflammation likely contributes to seizure development, and genetic variation in the interleukin‐1beta (IL‐1 β) gene, IL‐1β levels in cerebrospinal fluid and serum, and CSF/serum IL-1β ratios would predict PTE development post‐TBI.
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Chronic Inflammation After Severe Traumatic Brain Injury: Characterization and Associations With Outcome at 6 and 12 Months Postinjury.

TL;DR: The authors' subacute cytokine load score classifies individuals at risk for unfavorable outcomes following injury as higher proinflammatory burden with IL-6, relative to the anti-inflammatory marker IL-10, is significantly associated with outcome.