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Anais Vieira Da Cruz
Researcher at University of Grenoble
Publications - 4
Citations - 43
Anais Vieira Da Cruz is an academic researcher from University of Grenoble. The author has contributed to research in topics: Biology & Chemistry. The author has an hindex of 1, co-authored 1 publications receiving 12 citations.
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Polyhydroxylated Quinolizidine Iminosugars as Nanomolar Selective Inhibitors of α-Glucosidases
TL;DR: Polyhydroxylated quinolizidines bearing a hydroxymethyl group at the ring junction were synthesized from a readily available l-sorbose-derived ketonitrone and revealed to be potent and selective α-glucosidase inhibitors.
Journal ArticleDOI
Pyridylpiperazine-based allosteric inhibitors of RND-type multidrug efflux pumps
Coline Plé,H.K. Tam,Anais Vieira Da Cruz,Nina Compagne,Juan-Carlos Jiménez-Castellanos,Reinke T. Müller,Elizabeth Pradel,Wuen Ee Foong,Giuliano Malloci,Alexia Ballée,Moritz A. Kirchner,Parisa Moshfegh,Adrien Herledan,Andrea Herrmann,Benoit Deprez,Nicolas Willand,Attilio Vittorio Vargiu,Klaas M. Pos,Marion Flipo,Ruben C. Hartkoorn +19 more
TL;DR: In this paper , the authors identify and chemically optimize pyridylpiperazine-based compounds that potentiate antibiotic activity in E. coli through inhibition of its primary RND transporter, AcrAB-TolC.
Journal ArticleDOI
Update on the Discovery of Efflux Pump Inhibitors against Critical Priority Gram-Negative Bacteria
Nina Compagne,Anais Vieira Da Cruz,Reinke T. Müller,Ruben C. Hartkoorn,Marion Flipo,Klaas M. Pos +5 more
TL;DR: In this paper , the authors present eight families of efflux pump inhibitors (EPIs) active against Escherichia coli or Pseudomonas aeruginosa, and their binding sites and their mechanisms of action are analyzed comparatively.
Journal ArticleDOI
On the Hunt for Next-Generation Antimicrobial Agents: An Online Symposium Organized Jointly by the French Society for Medicinal Chemistry (Société de Chimie Thérapeutique) and the French Microbiology Society (Société Française de Microbiologie) on 9–10 December 2021
K. Antraygues,Nina Compagne,Francesca Gisella Zoe Ruggieri,Kamel Djaout,Zainab Edoo,Maxime Eveque,Léo Faïon,Bruna Gioia,Salia Tangara,Anais Vieira Da Cruz,Baptiste Villemagne,Marion Flipo,Alain R. Baulard,Nicolas Willand +13 more
TL;DR: The symposium generated high-level scientific dialogue on the most recent advances in combating antimicrobial resistance and attracted more than 200 researchers from France and abroad with interests in drug discovery, antimicrobial Resistance, medicinal chemistry, and related disciplines.