Showing papers by "Andrew J. Norton published in 1997"
01 Jan 1997
TL;DR: Between February 1989 and February 1995,122 patients with low-grade non-Hodgkin’s lymphoma received fludarabine: 25 mg/m2 daily for 5 days, repeated every 3-4 weeks, to a maximum of eight cycles.
Abstract: Between February 1989 and February 1995,122 patients with low-grade non-Hodgkin’s lymphoma received fludarabine: 25 mg/m2 daily for 5 days, repeated every 3-4 weeks, to a maximum of eight cycles. Eighty patients received fludarabine at first or subsequent recurrence, or when the disease was deemed resistant to conventional therapy, 26 patients were treated in the context of minimal residual disease (MRD) in the bone marrow and/or lymph nodes in the hope of eventually proceeding to myeloablative therapy with autologous bone marrow transplantation. A further 16 newly diagnosed patients received fludarabine as initial therapy.