Angelika C. Rueck

TL;DR: Human skin shows a strong autofluorescence in the red spectral region with main peaks around 600, 620, and 640 nm caused by the porphyrin production of the gram positive lipophile skin bacterium Propionibacterium acnes, and photodestruction of PropIONibacteria acnes by visible light appears to be a promising therapy.

TL;DR: In this article, Monte Carlo calculations were carried out to determine excitation and fluorescence photon distribution in case of red and violet excitation radiation, and the results showed the possibility of depth-resolved measurements on the fluorophore distribution by variation of excitation wavelength.

TL;DR: In this article, the authors present techniques and new perspectives of microscopic fluorescence spectroscopy in cellular diagnosis, including the detection of mitochondrial respiratory deficiencies and the intracellular location and light-induced reactions of photosensitizing porphyrins.

TL;DR: The first prerequisite for photodynamic therapy with chlorophyll-derived photosensitizers is irradiation at the S 1 absorption maximum in the red spectral region as mentioned in this paper, which changes its position due to molecular association by 20 to 100 nm depending on the subcellular environment, and must be determined by direct absorption spectrometry in the region of sub-cellular localization.

TL;DR: In this paper, the authors present techniques and new perspectives of microscopic fluorescence spectroscopy in cellular diagnosis, including the detection of mitochondrial respiratory deficiencies and of the intracellular locatio and light-induced reactions of photosensitizing porphyrins.