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Anne Cathrine Staff

Researcher at University of Oslo

Publications -  286
Citations -  11322

Anne Cathrine Staff is an academic researcher from University of Oslo. The author has contributed to research in topics: Pregnancy & Preeclampsia. The author has an hindex of 48, co-authored 242 publications receiving 8840 citations. Previous affiliations of Anne Cathrine Staff include Oslo University Hospital.

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IFPA Senior Award Lecture: making sense of pre-eclampsia - two placental causes of preeclampsia?

TL;DR: Normal placental perfusion and STB stress contribute to the pathogenesis of early and late onset pre-eclampsia, but the former has an extrinsic cause - poor placentation, whereas the latter has an intrinsic cause, 'microvillous overcrowding', as placental growth reaches its functional limits.
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Redefining preeclampsia using placenta-derived biomarkers.

TL;DR: The classic definitions of preeclampsia have become outdated and that the definition could be modernized to take account of the current understanding of disease pathophysiology, and a first step is proposed that incorporates the placental biomarker placenta growth factor (PlGF).
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Preeclampsia, biomarkers, syncytiotrophoblast stress, and placental capacity.

TL;DR: The maternal syndrome of preeclampsia mediated by dysfunctional syncytiotrophoblast (STB) signals are both proinflammatory and dysangiogenic such that the preeclamptic mother has a stronger vascular inflammatory response than normal as discussed by the authors.