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Anne H. Rowley

Researcher at Northwestern University

Publications -  136
Citations -  13125

Anne H. Rowley is an academic researcher from Northwestern University. The author has contributed to research in topics: Kawasaki disease & Pathogenesis. The author has an hindex of 46, co-authored 133 publications receiving 11368 citations. Previous affiliations of Anne H. Rowley include Loyola University Chicago & Children's Memorial Hospital.

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Immune pathogenesis of COVID-19-related multisystem inflammatory syndrome in children.

TL;DR: The need to elucidate the specific immune mechanisms underlying hyperinflammatory syndromes caused by SARS-CoV-2 to advance potential targeted treatments and prevention efforts is discussed.
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Activated myeloid dendritic cells accumulate and co-localize with CD3+ T cells in coronary artery lesions in patients with Kawasaki disease.

TL;DR: Coronary artery lesions of KD patients contain increased numbers of mature myeloid DCs with high HLA-DR expression and frequent T cell contacts detected immunohistochemically, which suggests that mature arterial myeloids DCs might be activating T cells in situ and may be a significant factor in the pathogenesis of coronary arteritis in KD.
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Patterns of Kawasaki syndrome presentation

TL;DR: A series of patients with Kawasaki syndrome are presented to illustrate its patterns of presentation and if a patient presents with unusual symptoms that are not consistent with the CDC guidelines, the diagnosis and treatment of KS can be delayed or even missed.
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Cloning the arterial IgA antibody response during acute Kawasaki disease.

TL;DR: This study synthesized a panel of mAbs from α and κ chain sequences present in the KD arterial wall and tested the Abs for binding to acute KD tissues, finding that all of the synthetic mAbs that bind to acute KP tissues detect Ag in cytoplasmic inclusion bodies in the acute KD ciliated bronchial epithelium.