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Anne-Lise Serre
Researcher at Institut national des sciences appliquées de Rouen
Publications - 2
Citations - 46
Anne-Lise Serre is an academic researcher from Institut national des sciences appliquées de Rouen. The author has contributed to research in topics: Chemical synthesis & Dihydroxylation. The author has an hindex of 2, co-authored 2 publications receiving 44 citations.
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Synthesis of α-CF2-mannosides and Their Conversion to Fluorinated Pseudoglycopeptides
TL;DR: A methodology allowing the synthesis alpha-CF(2)-mannosides, based on the addition of a difluoroenoxysilane to a glycal followed by a dihydroxylation reaction, is described, which converts into two pseudoglycopeptides which may act as E- and P-selectin inhibitors.
Journal ArticleDOI
Synthesis of fluorinated C-mannopeptides as sialyl Lewisx mimics for E- and P-selectin inhibition.
Vanessa Gouge-Ibert,Camille Pierry,Florent Poulain,Anne-Lise Serre,Céline Largeau,Virginie Escriou,Daniel Scherman,Philippe Jubault,Jean-Charles Quirion,Eric Leclerc +9 more
TL;DR: The synthesis of fluorinated C-mannopeptides and their evaluation as E- and P-selectin inhibitors is described, and these molecules showed inhibitory activities comparable to their CH(2) counterparts with a moderate influence of the pseudo-anomeric center configuration.