Annie Dutriaux

TL;DR: This map provides immediately available low-complexity cosmid material for high resolution FISH mapping of chromosomal aberrations on interphase nuclei, and for rapid positional isolation of transcripts in the highly resolved regions of genetic interest.

TL;DR: Investigation of the role of the VG–SD dimer in proliferation showed that vg antagonizes the effect of dacapo, the cyclin-cdk inhibitor and indicates that vG in interaction with dE2F1 and DHFR is a critical player for both cell proliferation and cell survival in the presumptive wing margin area.

TL;DR: The homology of this chromosome 21 duplicated region with the pericentromeric regions of chromosomes 13, 2, and 18 suggests that the mechanism involved is probably similar to pericentrumeric-directed mechanisms described in interchromosomal duplications.

TL;DR: The hypothesis that cell cycle genes fine‐tune wing growth and cell proliferation, in part, through control of the VG/SD stoichiometry and activity is supported, which points to a homeostatic feedback regulation between proliferation regulators and the VG–SD wing selector.

TL;DR: Fluorescence in situ hybridization on normal human chromosomes of YACs, cosmids, and phages positive with D21S190 confirmed the existence of two homologous regions on the long arm of chromosome 21 and characterized the region of homology.