The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

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Initial sequencing and analysis of the human genome.

Context. We present the second Gaia data release, Gaia DR2, consisting of astrometry, photometry, radial velocities, and information on astrophysical parameters and variability, for sources brighter than magnitude 21. In addition epoch astrometry and photometry are provided for a modest sample of minor planets in the solar system. Aims: A summary of the contents of Gaia DR2 is presented, accompanied by a discussion on the differences with respect to Gaia DR1 and an overview of the main limitations which are still present in the survey. Recommendations are made on the responsible use of Gaia DR2 results. Methods: The raw data collected with the Gaia instruments during the first 22 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into this second data release, which represents a major advance with respect to Gaia DR1 in terms of completeness, performance, and richness of the data products. Results: Gaia DR2 contains celestial positions and the apparent brightness in G for approximately 1.7 billion sources. For 1.3 billion of those sources, parallaxes and proper motions are in addition available. The sample of sources for which variability information is provided is expanded to 0.5 million stars. This data release contains four new elements: broad-band colour information in the form of the apparent brightness in the GBP (330-680 nm) and GRP (630-1050 nm) bands is available for 1.4 billion sources; median radial velocities for some 7 million sources are presented; for between 77 and 161 million sources estimates are provided of the stellar effective temperature, extinction, reddening, and radius and luminosity; and for a pre-selected list of 14 000 minor planets in the solar system epoch astrometry and photometry are presented. Finally, Gaia DR2 also represents a new materialisation of the celestial reference frame in the optical, the Gaia-CRF2, which is the first optical reference frame based solely on extragalactic sources. There are notable changes in the photometric system and the catalogue source list with respect to Gaia DR1, and we stress the need to consider the two data releases as independent. Conclusions: Gaia DR2 represents a major achievement for the Gaia mission, delivering on the long standing promise to provide parallaxes and proper motions for over 1 billion stars, and representing a first step in the availability of complementary radial velocity and source astrophysical information for a sample of stars in the Gaia survey which covers a very substantial fraction of the volume of our galaxy.

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Gaia Data Release 2. Summary of the contents and survey properties

Gaia is a cornerstone mission in the science programme of the EuropeanSpace Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the spacecraft and the payload were built by European industry. The involvement of the scientific community focusses on data processing for which the international Gaia Data Processing and Analysis Consortium (DPAC) was selected in 2007. Gaia was launched on 19 December 2013 and arrived at its operating point, the second Lagrange point of the Sun-Earth-Moon system, a few weeks later. The commissioning of the spacecraft and payload was completed on 19 July 2014. The nominal five-year mission started with four weeks of special, ecliptic-pole scanning and subsequently transferred into full-sky scanning mode. We recall the scientific goals of Gaia and give a description of the as-built spacecraft that is currently (mid-2016) being operated to achieve these goals. We pay special attention to the payload module, the performance of which is closely related to the scientific performance of the mission. We provide a summary of the commissioning activities and findings, followed by a description of the routine operational mode. We summarise scientific performance estimates on the basis of in-orbit operations. Several intermediate Gaia data releases are planned and the data can be retrieved from the Gaia Archive, which is available through the Gaia home page.

The Gaia mission

On September 14, 2015 at 09:50:45 UTC the two detectors of the Laser Interferometer Gravitational-Wave Observatory simultaneously observed a transient gravitational-wave signal. The signal sweeps upwards in frequency from 35 to 250 Hz with a peak gravitational-wave strain of 1.0×10(-21). It matches the waveform predicted by general relativity for the inspiral and merger of a pair of black holes and the ringdown of the resulting single black hole. The signal was observed with a matched-filter signal-to-noise ratio of 24 and a false alarm rate estimated to be less than 1 event per 203,000 years, equivalent to a significance greater than 5.1σ. The source lies at a luminosity distance of 410(-180)(+160)  Mpc corresponding to a redshift z=0.09(-0.04)(+0.03). In the source frame, the initial black hole masses are 36(-4)(+5)M⊙ and 29(-4)(+4)M⊙, and the final black hole mass is 62(-4)(+4)M⊙, with 3.0(-0.5)(+0.5)M⊙c(2) radiated in gravitational waves. All uncertainties define 90% credible intervals. These observations demonstrate the existence of binary stellar-mass black hole systems. This is the first direct detection of gravitational waves and the first observation of a binary black hole merger.

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The Observation of Gravitational Waves from a Binary Black Hole Merger

The genome of the yeast Saccharomyces cerevisiae has been completely sequenced through a worldwide collaboration. The sequence of 12,068 kilobases defines 5885 potential protein-encoding genes, approximately 140 genes specifying ribosomal RNA, 40 genes for small nuclear RNA molecules, and 275 transfer RNA genes. In addition, the complete sequence provides information about the higher order organization of yeast's 16 chromosomes and allows some insight into their evolutionary history. The genome shows a considerable amount of apparent genetic redundancy, and one of the major problems to be tackled during the next stage of the yeast genome project is to elucidate the biological functions of all of these genes.

Life with 6000 Genes

Abstract OB associations are prime sites for the study of star formation processes and of the interaction between young massive stars with the interstellar medium. Furthermore, the kinematics and structure of the nearest OB associations provide detailed insight into the properties and origin of the Gould Belt. In this context, the Orion complex has been extensively studied. However, the spatial distribution of the stellar population is still uncertain: in particular, the distances and ages of the various sub-groups composing the Orion OB association, and their connection to the surrounding interstellar medium, are not well determined. We used the first Gaia data release to characterize the stellar population in Orion, with the goal to obtain new distance and age estimates of the numerous stellar groups composing the Orion OB association. We found evidence of the existence of a young and rich population spread over the entire region, loosely clustered around some known groups. This newly discovered population of young stars provides a fresh view of the star formation history of the Orion region.

Mapping young stellar populations towards Orion with Gaia DR1

We address the problem of identifying remnants of satellite galaxies in the halo of our galaxy with Gaia data. We make use of N-body simulations of dwarf galaxies being disrupted in the halo of our galaxy combined with a Monte Carlo model of the Milky Way galaxy. The models are converted to a simulated Gaia catalogue containing a realistic number ($\sim10^8$--$10^9$) of stars. The simulated catalogue can be used to study how to handle the large data set that Gaia will provide and to study issues such as how to best retrieve information on substructure in the Galactic halo. The techniques described are applicable to any set of N-body simulations of (parts of) the Galaxy.

From Detailed Galaxy Simulations to a Realistic End-of-Mission Gaia Catalogue

If we want to understand the evolution from star clusters to the Galactic field star population, the Solar neighbourhood is an ideal place to start. It contains objects from dense, very young clusters to old and almost dissolved moving groups. I describe the observational evidence for the ongoing dissolution of OB associations and open clusters. Subsequently, the interpretation of the local phase space distribution of stars in terms of old moving groups is discussed, emphasising the present limitations. Finally, I discuss future observational requirements and the possibilities offered by upcoming astrometric space missions.

Evolution from OB Associations and Moving Groups to the Field Population

Simeis 57 (HS 191) is an optically bright nebula in the Cygnus X region with a peculiar appearance that suggests an outflow from a rotating source. Newly obtained observations and archival data reveal Simeis 57 as a low-density ($n_{e}\,\sim\,100$ cm$^{-3}$) nebula with an east-to-west excitation gradient. The extinction of the nebula is $A_{V}\,\leq$ 2 mag. The nebula is recognizable but not prominent in mid- and far-infrared images. In its direction, half a dozen small CO clouds have been identified at $V_{LSR}$ = + 5 km s$^{-1}$. One of these coincides with both the optical nebula and a second CO cloud at the nebular velocity $V_{LSR}\,\approx$ -10 km $^{-1}$. No luminous stars are embedded in these molecular clouds, nor are any obscured by them and no sufficiently luminous stars are found in the immediate vicinity of the nebula. Instead, all available data points to the evolved star HD 193793 = WR 140 (an O4-5 supergiant and WC7 Wolf-Rayet binary) as the source of excitation, notwithstanding its large separation of $50'$, about 25 pc at the stellar distance of 1.7 kpc. Simeis 57 appears to be a part of a larger structure surrounding the HI void centered on HD 193793.

The peculiar nebula Simeis 57: II. Distance, nature and excitation

This contribution is intended as a ‘rough guide’ to the Hipparcos Catalogue for the non-expert user. Some general aspects of the use of astrometric data are discussed as well as Hipparcos-specific applications. We discuss when and at what level one may expect systematic errors to occur in the Hipparcos Catalogue. Next we discuss the question of the interpretation of the measured parallaxes in terms of distances and luminosities of stars. What are the biases one should be aware of and how can these be corrected? When using the astrometric data to study the statistics of stars one should take the full covariance matrix of the errors on the astrometric parameters into account. We explain how to do this and discuss the specific case of a moving cluster. Finally, we address the question of the correlation of astrometric parameters over a given region of the sky. At present the Hipparcos Catalogue contains no identified systematic errors.

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Anthony G. A. Brown

Papers

Mapping young stellar populations towards Orion with Gaia DR1

From Detailed Galaxy Simulations to a Realistic End-of-Mission Gaia Catalogue

Evolution from OB Associations and Moving Groups to the Field Population

The peculiar nebula Simeis 57: II. Distance, nature and excitation

Some Considerations in Making Full Use of The HIPPARCOS Catalogue