The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

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Initial sequencing and analysis of the human genome.

Context. We present the second Gaia data release, Gaia DR2, consisting of astrometry, photometry, radial velocities, and information on astrophysical parameters and variability, for sources brighter than magnitude 21. In addition epoch astrometry and photometry are provided for a modest sample of minor planets in the solar system. Aims: A summary of the contents of Gaia DR2 is presented, accompanied by a discussion on the differences with respect to Gaia DR1 and an overview of the main limitations which are still present in the survey. Recommendations are made on the responsible use of Gaia DR2 results. Methods: The raw data collected with the Gaia instruments during the first 22 months of the mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC) and turned into this second data release, which represents a major advance with respect to Gaia DR1 in terms of completeness, performance, and richness of the data products. Results: Gaia DR2 contains celestial positions and the apparent brightness in G for approximately 1.7 billion sources. For 1.3 billion of those sources, parallaxes and proper motions are in addition available. The sample of sources for which variability information is provided is expanded to 0.5 million stars. This data release contains four new elements: broad-band colour information in the form of the apparent brightness in the GBP (330-680 nm) and GRP (630-1050 nm) bands is available for 1.4 billion sources; median radial velocities for some 7 million sources are presented; for between 77 and 161 million sources estimates are provided of the stellar effective temperature, extinction, reddening, and radius and luminosity; and for a pre-selected list of 14 000 minor planets in the solar system epoch astrometry and photometry are presented. Finally, Gaia DR2 also represents a new materialisation of the celestial reference frame in the optical, the Gaia-CRF2, which is the first optical reference frame based solely on extragalactic sources. There are notable changes in the photometric system and the catalogue source list with respect to Gaia DR1, and we stress the need to consider the two data releases as independent. Conclusions: Gaia DR2 represents a major achievement for the Gaia mission, delivering on the long standing promise to provide parallaxes and proper motions for over 1 billion stars, and representing a first step in the availability of complementary radial velocity and source astrophysical information for a sample of stars in the Gaia survey which covers a very substantial fraction of the volume of our galaxy.

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Gaia Data Release 2. Summary of the contents and survey properties

Gaia is a cornerstone mission in the science programme of the EuropeanSpace Agency (ESA). The spacecraft construction was approved in 2006, following a study in which the original interferometric concept was changed to a direct-imaging approach. Both the spacecraft and the payload were built by European industry. The involvement of the scientific community focusses on data processing for which the international Gaia Data Processing and Analysis Consortium (DPAC) was selected in 2007. Gaia was launched on 19 December 2013 and arrived at its operating point, the second Lagrange point of the Sun-Earth-Moon system, a few weeks later. The commissioning of the spacecraft and payload was completed on 19 July 2014. The nominal five-year mission started with four weeks of special, ecliptic-pole scanning and subsequently transferred into full-sky scanning mode. We recall the scientific goals of Gaia and give a description of the as-built spacecraft that is currently (mid-2016) being operated to achieve these goals. We pay special attention to the payload module, the performance of which is closely related to the scientific performance of the mission. We provide a summary of the commissioning activities and findings, followed by a description of the routine operational mode. We summarise scientific performance estimates on the basis of in-orbit operations. Several intermediate Gaia data releases are planned and the data can be retrieved from the Gaia Archive, which is available through the Gaia home page.

The Gaia mission

On September 14, 2015 at 09:50:45 UTC the two detectors of the Laser Interferometer Gravitational-Wave Observatory simultaneously observed a transient gravitational-wave signal. The signal sweeps upwards in frequency from 35 to 250 Hz with a peak gravitational-wave strain of 1.0×10(-21). It matches the waveform predicted by general relativity for the inspiral and merger of a pair of black holes and the ringdown of the resulting single black hole. The signal was observed with a matched-filter signal-to-noise ratio of 24 and a false alarm rate estimated to be less than 1 event per 203,000 years, equivalent to a significance greater than 5.1σ. The source lies at a luminosity distance of 410(-180)(+160)  Mpc corresponding to a redshift z=0.09(-0.04)(+0.03). In the source frame, the initial black hole masses are 36(-4)(+5)M⊙ and 29(-4)(+4)M⊙, and the final black hole mass is 62(-4)(+4)M⊙, with 3.0(-0.5)(+0.5)M⊙c(2) radiated in gravitational waves. All uncertainties define 90% credible intervals. These observations demonstrate the existence of binary stellar-mass black hole systems. This is the first direct detection of gravitational waves and the first observation of a binary black hole merger.

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The Observation of Gravitational Waves from a Binary Black Hole Merger

The genome of the yeast Saccharomyces cerevisiae has been completely sequenced through a worldwide collaboration. The sequence of 12,068 kilobases defines 5885 potential protein-encoding genes, approximately 140 genes specifying ribosomal RNA, 40 genes for small nuclear RNA molecules, and 275 transfer RNA genes. In addition, the complete sequence provides information about the higher order organization of yeast's 16 chromosomes and allows some insight into their evolutionary history. The genome shows a considerable amount of apparent genetic redundancy, and one of the major problems to be tackled during the next stage of the yeast genome project is to elucidate the biological functions of all of these genes.

Life with 6000 Genes

In the context of the luminosity calibration of the nearer stars I discuss the Hipparcos results on distances to nearby OB associations and open clusters. The shortcomings and assumptions in the analyses used to derive these results are pointed out and for the open clusters a comparison is made with results obtained from main sequence fitting. I conclude that given the considerable uncertainties in the latter technique there is no convincing evidence that the Hipparcos based distances to open clusters beyond the Hyades should not be trusted.

OB Associations, Open Clusters, and the Luminosity Calibration of the Nearer Stars

The structure and evolution of OB associations

In this contribution I provide an overview of the the European Space Agency's Gaia mission just ahead of its launch scheduled for November 2013

Gaia, counting down to launch

We present the first results of a comprehensive census of the stellar content of the nearby OB associations based on Hipparcos positions, proper motions and parallaxes for 12842 candidate member stars distributed over 21 fields on the sky. We use a new method to identify moving groups in these fields (see de Bruijne et al., these proceedings). Previously, astrometric membership in nearly all the nearby OB associations was known only for stars with spectral types earlier than B5. The Hipparcos measurements now allow us to identify members down to late F. This census provides a firm basis for studies of galactic and extragalactic star forming regions.

https://arxiv.org/pdf/astro-ph/9707089.pdf

Structure and Evolution of Nearby OB Associations

Simeis 57 (HS 191) is an optically bright nebula in the Cygnus X region with a peculiar appearance that suggests an outflow from a rotating source. Newly obtained observations and archival data reveal Simeis 57 as a low-density (n e ~ 100 cm−3 ) nebula with an east-to-west excitation gradient. The extinction of the nebula is A V ≤ 2 mag. The nebula is recognizable but not prominent in mid- and far-infrared images. In its direction, half a dozen small CO clouds have been identified at V LSR = +5 km s−1 . One of these coincides with both the optical nebula and a second CO cloud at the nebular velocity V LSR ≈−10 km−1 . No luminous stars are embedded in these molecular clouds, nor are any obscured by them and no sufficiently luminous stars are found in the immediate vicinity of the nebula. Instead, all available data points to the evolved star HD 193793 = WR 140 (an O4-5 supergiant and WC7 Wolf–Rayet binary) as the source of excitation, notwithstanding its large separation of 50′, about 25 pc at the stellar distance of 1.7 kpc. Simeis 57 appears to be a part of a larger structure surrounding the HI void centered on HD 193793.

Anthony G. A. Brown

Papers

OB Associations, Open Clusters, and the Luminosity Calibration of the Nearer Stars

The structure and evolution of OB associations

Gaia, counting down to launch

Structure and Evolution of Nearby OB Associations

The peculiar nebula Simeis 57 - II. Distance, nature and excitation