Data Mining - Concepts and Techniques.

The 11th edition of Harrison's Principles of Internal Medicine welcomes Anthony Fauci to its editorial staff, in addition to more than 85 new contributors. While the organization of the book is similar to previous editions, major emphasis has been placed on disorders that affect multiple organ systems. Important advances in genetics, immunology, and oncology are emphasized. Many chapters of the book have been rewritten and describe major advances in internal medicine. Subjects that received only a paragraph or two of attention in previous editions are now covered in entire chapters. Among the chapters that have been extensively revised are the chapters on infections in the compromised host, on skin rashes in infections, on many of the viral infections, including cytomegalovirus and Epstein-Barr virus, on sexually transmitted diseases, on diabetes mellitus, on disorders of bone and mineral metabolism, and on lymphadenopathy and splenomegaly. The major revisions in these chapters and many

Harrison's Principles of Internal Medicine

International Journal of Computer and Applications

IEEE Transactions on Pattern Analysis and Machine Intelligence

Curcumin is the active ingredient in the traditional herbal remedy and dietary spice turmeric (Curcuma longa). Curcumin has a surprisingly wide range of beneficial properties, including anti-inflammatory, antioxidant, chemopreventive and chemotherapeutic activity. The pleiotropic activities of curcumin derive from its complex chemistry as well as its ability to influence multiple signaling pathways, including survival pathways such as those regulated by NF-κB, Akt, and growth factors; cytoprotective pathways dependent on Nrf2; and metastatic and angiogenic pathways. Curcumin is a free radical scavenger and hydrogen donor, and exhibits both pro- and antioxidant activity. It also binds metals, particularly iron and copper, and can function as an iron chelator. Curcumin is remarkably non-toxic and exhibits limited bioavailability. Curcumin exhibits great promise as a therapeutic agent, and is currently in human clinical trials for a variety of conditions, including multiple myeloma, pancreatic cancer, myelodysplastic syndromes, colon cancer, psoriasis and Alzheimer’s disease.

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Curcumin: From ancient medicine to current clinical trials

This paper describes the database development of three different types of spoken words Isolated, Spoken Hindi Hybrid Paired Words and Spoken Hindi Partially Reduplicated words. The main focus is on the comparative analysis of these Words by using endpoint detection algorithm. The development is done in the robust environment. Different male and female speakers are selected and recording is done in normal mode. Endpoint detection algorithm is used for the analysis purpose of various parameters such as Total duration of time, Number of samples, Root mean square value and Mean power (Intensity) in air of speech signal.

Database Development and Comparative Analysis of Isolated, Spoken Hindi Hybrid Paired Words & Spoken Hindi Partially Reduplicated Words Using Endpoint Detection

Abstract Purpose To report a case of a rare disease entity Posterior Microphthalmos Pigmentary Retinopathy Syndrome (PMPRS) in a 47-year-old female with a brief review of literature. Case Report A 47-year-old woman presented with a history of defective vision with an associated difficulty in night vision. Clinical workup was done, which included a thorough ocular examination showing diffuse pigmentary mottling of fundus, ocular biometry showing short axial length with normal anterior segment dimensions, electroretinography showing extinguished response, optical coherence tomography showing foveoschisis, and ultrasonography showing thickened sclera–choroidal complex. Findings were consistent with those reported by other authors with PMPRS. Conclusion Posterior microphthalmia with or without other ocular and systemic associations should be suspected in cases with high hyperopia. It is mandatory to carefully examine the patient at presentation and close follow-ups are needed to maintain visual function.

https://knepublishing.com/index.php/JOVR/article/download/13190/21348

Posterior Microphthalmos Pigmentary Retinopathy Syndrome

Four new azo-based supramolecular materials containing thiacalixarene core substituted by variable alkoxy group (TFA1-TFA4) have been designed and synthesized for the mesomorphic and photoswitching properties. The liquid crystalline behavior were accomplished by using DSC, POM, and XRD studies. All azo-based thiacalixarene based materials with short and higher chain length display columnar hexagonal mesophase with broad temperature range. The thermal behavior of all the materials was investigated by DSC and TGA study. The structural and conformational study of the lower rim functinoazlized materials was confirmed by using different techniques. These thiacalixarene moulded liquid crystalline compound shows columnar self-assembly type behavior and higher thermal stability. The introduction of bi-substituted azo-ester network towards the lower rim of thiacalixarene core has impact on the electron delocalization and liquid crystalline properties. The photoswitching properties suggested cis and trans azo-isomerization under radiation of UV light and higher thermal back relaxation time. The mesogenic behaviour of compound TFA2 and TFA4were demolished by the influence of cis and trans isomerization. The structure-property correlation is study to understand the variation of mesogenic properties with the substitution of variable alkoxy side chain.

Thiacalixarene Appended Azo-based Supramolecular Systems: Self-assembly and Photo Tuning Reversible Liquid Crystalline Properties.

A Convenient Synthetic Route for Alkynyl Selenides from Alkynyl Bromides and Diaryl Diselenides Employing Copper(I)/Imidazole as Novel Catalyst System.

Businesses are increasingly preparing for remote working by equipping managers and their teams with the necessary tools and technology. This research focuses on understanding how technology–enabled remote working practices are implemented and normalized, taking into consideration the context in which they are applied. By utilizing process virtualization theory (PVT) to quantitatively evaluate context-dependent factors and normalization process theory (NPT) to explore the normalization of new technology-driven remote work practices, this study investigates the static and dynamic factors affecting the virtualization of remote work processes, as well as their implementation and normalization. The results from multiple surveys reveal that sensory requirements along with relationship requirements and control requirements are dynamic factors that are driven by the context and enable the technology–enabled virtualization of remote work processes. Furthermore, the relative normalization of this work transformation is sustained through flexible co–construction, legitimation, contextual integration, and effective leadership. 

Anuj Sharma

Papers

Database Development and Comparative Analysis of Isolated, Spoken Hindi Hybrid Paired Words & Spoken Hindi Partially Reduplicated Words Using Endpoint Detection

Posterior Microphthalmos Pigmentary Retinopathy Syndrome

Thiacalixarene Appended Azo-based Supramolecular Systems: Self-assembly and Photo Tuning Reversible Liquid Crystalline Properties.

A Convenient Synthetic Route for Alkynyl Selenides from Alkynyl Bromides and Diaryl Diselenides Employing Copper(I)/Imidazole as Novel Catalyst System.

Process Virtualization Goes Mainstream: Diving into its Normalization