Showing papers by "Anunciación Lafuente published in 1999"
TL;DR: The accumulative data indicates the existence of a disruption in the regulatory mechanisms of the hypothalamic-pituitary axis and the physiological significance of these effects remains to be elucidated.
75 citations
TL;DR: It is indicated that low doses of cadmium change the pulsatile secretion of LH in male rats and that the effect of Cadmium on episodic LH release was age-dependent.
30 citations
TL;DR: It is suggested that subchronic cadmium exposure changes the secretory pattern of prolactin in adult male rats in a puberty-dependent way.
Abstract: This work was undertaken to assess if exposure to cadmium related to puberty may affect the episodic pattern of prolactin. Male rats were submitted to cadmium exposure, from day 30 to 60 or from day 60 to 90 of life respectively, at a dose of 50 ppm in the drinking water. Control age-matched rats received cadmium-free water. Prepubertal cadmium administration decreased mean serum prolactin levels and the absolute amplitude of the prolactin pulses. Subchronic exposure to cadmium of adult rats decreased mean serum prolactin levels, the absolute amplitude of the prolactin pulses and their duration, and the mean half-life of the hormone. These results suggest that subchronic cadmium exposure changes the secretory pattern of prolactin in adult male rats in a puberty-dependent way.
10 citations