Anwesha Sanyal

TL;DR: The size of the inducible, replication-competent latent HIV-1 reservoir in aviremic participants on therapy is approximately 70-fold larger than previous estimates.

TL;DR: Electron micrograph morphology of the Leishman-Donovan body occurring in a nodular lesion of dermal leishmanoid has been described and the possible functional, cytochemical and morphogenetic implications of the structural pattern have been considered.

TL;DR: Collectively, this study describes a chemical approach that can be applied to elucidate the role of signaling pathways involved in LRA activity or the maintenance of HIV-1 latency and identifies inhibitors of latent HIV- 1 reactivation that could be used with antiretroviral therapy to reduce residual viremia.

TL;DR: A potentially novel human immune system-humanized mouse model by coengrafting autologous fetal thymus, spleen, and liver organoids under the kidney capsule, thus termed the BM-liver-thymus-spleen (BLTS) humanized mice model, which will enable in vivo mechanistic studies and complementing the well-established surrogate model of SIV infection-induced lymphoid tissue fibrosis in macaques.

TL;DR: It is suggested that HCV transmission and evolution in HIV-infected subjects may not be influenced by host CD4 cell count at the time of infection.