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April C. Childs
Researcher at University of Florida
Publications - 3
Citations - 931
April C. Childs is an academic researcher from University of Florida. The author has contributed to research in topics: Oxidative stress & Apoptosis. The author has an hindex of 3, co-authored 3 publications receiving 889 citations.
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Journal Article
Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio.
TL;DR: It is demonstrated that doxorubicin induces oxidative stress and mitochondrial-mediated apoptosis, as well as adaptive responses by the mitochondria to protect cardiac myocytes in vivo.
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Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise.
TL;DR: This acute human inflammatory model strongly suggests that vitamin C and NAC supplementation immediately post-injury, transiently increases tissue damage and oxidative stress.
Journal ArticleDOI
A dietary supplement attenuates IL-6 and CRP after eccentric exercise in untrained males
TL;DR: It is suggested that exercise-induced inflammation, evaluated by changes in IL-6 and CRP, was significantly reduced by the dietary supplement.