A
Ara Cho
Researcher at Yonsei University
Publications - 6
Citations - 548
Ara Cho is an academic researcher from Yonsei University. The author has contributed to research in topics: Gene & Gene regulatory network. The author has an hindex of 6, co-authored 6 publications receiving 431 citations.
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TRRUST: a reference database of human transcriptional regulatory interactions
Heonjong Han,Hongseok Shim,Donghyun Shin,Jung Eun Shim,Yunhee Ko,Junha Shin,Hanhae Kim,Ara Cho,Eiru Kim,Tak Lee,Hyo-Jin Kim,Kyung Soo Kim,Sunmo Yang,Dasom Bae,Ayoung Yun,Sunphil Kim,Chan Yeong Kim,Hyeon Jin Cho,Byunghee Kang,Susie Shin,Insuk Lee +20 more
TL;DR: A database of literature-curated human TF-target interactions, TRRUST (transcriptional regulatory relationships unravelled by sentence-based text-mining, http://www.grnpedia.org/trrust), which currently contains 8,015 interactions between 748 TF genes and 1,975 non-TF genes is presented.
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MUFFINN: cancer gene discovery via network analysis of somatic mutation data
TL;DR: A method for prioritizing cancer genes accounting not only for mutations in individual genes but also in their neighbors in functional networks, MUFFINN (MUtations For Functional Impact on Network Neighbors), which shows high sensitivity compared with gene-centric analyses of mutation data.
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WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans
Ara Cho,Junha Shin,Sohyun Hwang,Chanyoung Kim,Hongseok Shim,Hyo-Jin Kim,Hanhae Kim,Insuk Lee +7 more
TL;DR: WormNet version 3 (v3), which is a new network-assisted hypothesis-generating server for C. elegans, includes major updates to the base gene network, which substantially improved predictions of RNAi phenotypes.
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Network-assisted investigation of virulence and antibiotic-resistance systems in Pseudomonas aeruginosa.
Sohyun Hwang,Chan Yeong Kim,Sun-Gou Ji,Junhyeok Go,Hanhae Kim,Sunmo Yang,Hye Jin Kim,Ara Cho,Sang Sun Yoon,Insuk Lee +9 more
TL;DR: It is demonstrated that the usefulness of a genome-scale functional network to investigate pathogenic systems in P. aeruginosa can be demonstrated, and PseudomonasNet-assisted predictions can effectively identify novel genes involved in virulence and antibiotic resistance.
Journal ArticleDOI
FlyNet: a versatile network prioritization server for the Drosophila community
Junha Shin,Sunmo Yang,Eiru Kim,Chan Yeong Kim,Hongseok Shim,Ara Cho,Hyo-Jin Kim,Sohyun Hwang,Jung Eun Shim,Insuk Lee +9 more
TL;DR: A network prioritization server dedicated to Drosophila that covers ∼95% of the coding genome and is expected to serve as a versatile hypothesis-generation platform for genes and functions in the study of basic animal genetics, developmental biology and human disease.