A
Arabinda Samanta
Publications - 1
Citations - 307
Arabinda Samanta is an academic researcher. The author has contributed to research in topics: Transfection. The author has an hindex of 1, co-authored 1 publications receiving 271 citations.
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Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale
Martin Lock,Mauricio R. Alvira,Luk H. Vandenberghe,Arabinda Samanta,Jaan Toelen,Zeger Debyser,James M. Wilson +6 more
TL;DR: A high-yielding, recombinant AAV production process based on polyethylenimine-mediated transfection of HEK293 cells and iodixanol gradient centrifugation of concentrated culture supernatant is described, demonstrating equivalent or better transduction both in vitro and in vivo when compared with small-scale, CsCl gradient-purified vectors.