A
Archana Padmanabhan Nair
Researcher at Manipal University
Publications - 23
Citations - 235
Archana Padmanabhan Nair is an academic researcher from Manipal University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 13 publications receiving 59 citations.
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Journal ArticleDOI
Dysregulated Tear Fluid Nociception-Associated Factors, Corneal Dendritic Cell Density, and Vitamin D Levels in Evaporative Dry Eye.
Pooja Khamar,Archana Padmanabhan Nair,Rohit Shetty,Tanuja Vaidya,Murali Subramani,Murugeswari Ponnalagu,Kamesh Dhamodaran,Sharon D'Souza,Anuprita Ghosh,Natasha Pahuja,Rashmi Deshmukh,Prerna Ahuja,Kanchan Sainani,Rudy M.M.A. Nuijts,Debashish Das,Arkasubhra Ghosh,Swaminathan Sethu +16 more
TL;DR: Altered tear fluid soluble factors with potential to modulate nociception exhibited a distinct association with ocular surface discomfort status, TBUT, STI, and cDCD, implying a functional relationship between the various tear-soluble factors and dry eye pathogenesis, indicating new molecular targets for designing targeted therapies.
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Genistein-Calcitriol Mitigates Hyperosmotic Stress-Induced TonEBP, CFTR Dysfunction, VDR Degradation and Inflammation in Dry Eye Disease.
Trailokyanath Panigrahi,Sharon D'Souza,Rohit Shetty,Archana Padmanabhan Nair,Anuprita Ghosh,Everette Jacob Remington Nelson,Arkasubhra Ghosh,Swaminathan Sethu +7 more
TL;DR: Significantly, higher expression of inflammatory factors, TonEBP, GLRX5, and reduced VDR were observed in patients with DED and in HOs‐induced HCECs in vitro, which suggests dysregulated OS homeostasis in DED.
Journal ArticleDOI
Pain management after photorefractive keratectomy.
Rohit Shetty,Ritika Dalal,Archana Padmanabhan Nair,Pooja Khamar,Sharon D'Souza,Ravish Vaishnav +5 more
TL;DR: The UHPLC results showed that the soaked bandage contact lens acted as a depot for ketorolac, which was released onto the ocular surface over time, providing postoperative pain relief without causing adverse events.
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Increased LCN2 (lipocalin 2) in the RPE decreases autophagy and activates inflammasome-ferroptosis processes in a mouse model of dry AMD
Urvi Gupta,Sayan Ghosh,Callen T. Wallace,Peng Zhang,Ying Xin,Archana Padmanabhan Nair,Meysam Yazdankhah,A. Strizhakova,Mark A. Ross,Haitao Liu,Stacey Hose,Nadezda A. Stepicheva,Olivia Chowdhury,Mihi Nemani,Vishnu Maddipatla,Rhonda Grebe,Manjula Das,K Lathrop,José-Alain Sahel,J. Samuel Zigler,Jiang Qian,Arkasubhra Ghosh,Yuri V. Sergeev,James T. Handa,Claudette M. St. Croix,Debasish Sinha +25 more
TL;DR: A molecular pathway whereby increased LCN2 elicits pathophysiology in the RPE, cells known to drive dry AMD pathology is identified, thus providing a possible therapeutic strategy for a disease with no current treatment options.
Journal ArticleDOI
Potential ocular and systemic COVID-19 prophylaxis approaches for healthcare professionals.
Rohit Shetty,Vaitheeswaran Ganesan Lalgudi,Pooja Khamar,Krati Gupta,Swaminathan Sethu,Archana Padmanabhan Nair,Santosh G Honavar,Arkasubhra Ghosh,Sharon D'Souza +8 more
TL;DR: Additional prophylactic measures including drug repurposing or new indication paradigms to render protection, including chloroquine, trehalose, antihistaminics, and interferons used topically for various ocular conditions with reasonably good safety records are discussed.