The Probable and the Provable

Proceedings of the 2012 Joint Conference on Empirical Methods in Natural Language Processing and Computational Natural Language Learning

Background: Web-based sources are increasingly employed in the analysis, detection, and forecasting of diseases and epidemics, and in predicting human behavior toward several health topics. This use of the internet has come to be known as infodemiology, a concept introduced by Gunther Eysenbach. Infodemiology and infoveillance studies use web-based data and have become an integral part of health informatics research over the past decade.
Objective: The aim of this paper is to provide a scoping review of the state-of-the-art in infodemiology along with the background and history of the concept, to identify sources and health categories and topics, to elaborate on the validity of the employed methods, and to discuss the gaps identified in current research.
Methods: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were followed to extract the publications that fall under the umbrella of infodemiology and infoveillance from the JMIR, PubMed, and Scopus databases. A total of 338 documents were extracted for assessment.
Results: Of the 338 studies, the vast majority (n=282, 83.4%) were published with JMIR Publications. The Journal of Medical Internet Research features almost half of the publications (n=168, 49.7%), and JMIR Public Health and Surveillance has more than one-fifth of the examined studies (n=74, 21.9%). The interest in the subject has been increasing every year, with 2018 featuring more than one-fourth of the total publications (n=89, 26.3%), and the publications in 2017 and 2018 combined accounted for more than half (n=171, 50.6%) of the total number of publications in the last decade. The most popular source was Twitter with 45.0% (n=152), followed by Google with 24.6% (n=83), websites and platforms with 13.9% (n=47), blogs and forums with 10.1% (n=34), Facebook with 8.9% (n=30), and other search engines with 5.6% (n=19). As for the subjects examined, conditions and diseases with 17.2% (n=58) and epidemics and outbreaks with 15.7% (n=53) were the most popular categories identified in this review, followed by health care (n=39, 11.5%), drugs (n=40, 10.4%), and smoking and alcohol (n=29, 8.6%).
Conclusions: The field of infodemiology is becoming increasingly popular, employing innovative methods and approaches for health assessment. The use of web-based sources, which provide us with information that would not be accessible otherwise and tackles the issues arising from the time-consuming traditional methods, shows that infodemiology plays an important role in health informatics research.

/pdf/infodemiology-and-infoveillance-scoping-review-1llfmlaet2.pdf

Infodemiology and Infoveillance: Scoping Review

Exploring the boundaries of open innovation: Evidence from social media mining

Social media have become a common way for people to express their personal viewpoints, including sentiments about health topics. We present the results of an opinion mining analysis on vaccination ...

https://www.tandfonline.com/doi/pdf/10.1080/21645515.2020.1714311

Twitter as a sentinel tool to monitor public opinion on vaccination: an opinion mining analysis from September 2016 to August 2017 in Italy.

The global growth of social media usage over the past decade has opened research avenues for mining health related information that can ultimately be used to improve public health. The Social Media Mining for Health Applications (#SMM4H) shared tasks in its sixth iteration sought to advance the use of social media texts such as Twitter for pharmacovigilance, disease tracking and patient centered outcomes. #SMM4H 2021 hosted a total of eight tasks that included reruns of adverse drug effect extraction in English and Russian and newer tasks such as detecting medication non-adherence from Twitter and WebMD forum, detecting self-reported adverse pregnancy outcomes, detecting cases and symptoms of COVID-19, identifying occupations mentioned in Spanish by Twitter users, and detecting self-reported breast cancer diagnosis. The eight tasks included a total of 12 individual subtasks spanning three languages requiring methods for binary classification, multi-class classification, named entity recognition and entity normalization. With a total of 97 registering teams and 40 teams submitting predictions, the interest in the shared tasks grew by 70% and participation grew by 38% compared to the previous iteration.

/pdf/overview-of-the-sixth-social-media-mining-for-health-4dlc0uzui3.pdf

Overview of the Sixth Social Media Mining for Health Applications (#SMM4H) Shared Tasks at NAACL 2021

Background: Pregnancy exposure registries are the primary sources of information about the safety of maternal usage of medications during pregnancy. Such registries enroll pregnant women in a voluntary fashion early on in pregnancy and follow them until the end of pregnancy or longer to systematically collect information regarding specific pregnancy outcomes. Although the model of pregnancy registries has distinct advantages over other study designs, they are faced with numerous challenges and limitations such as low enrollment rate, high cost, and selection bias. Objective: The primary objectives of this study were to systematically assess whether social media (Twitter) can be used to discover cohorts of pregnant women and to develop and deploy a natural language processing and machine learning pipeline for the automatic collection of cohort information. In addition, we also attempted to ascertain, in a preliminary fashion, what types of longitudinal information may potentially be mined from the collected cohort information. Methods: Our discovery of pregnant women relies on detecting pregnancy-indicating tweets (PITs), which are statements posted by pregnant women regarding their pregnancies. We used a set of 14 patterns to first detect potential PITs. We manually annotated a sample of 14,156 of the retrieved user posts to distinguish real PITs from false positives and trained a supervised classification system to detect real PITs. We optimized the classification system via cross validation, with features and settings targeted toward optimizing precision for the positive class. For users identified to be posting real PITs via automatic classification, our pipeline collected all their available past and future posts from which other information (eg, medication usage and fetal outcomes) may be mined. Results: Our rule-based PIT detection approach retrieved over 200,000 posts over a period of 18 months. Manual annotation agreement for three annotators was very high at kappa (κ)=.79. On a blind test set, the implemented classifier obtained an overall F1 score of 0.84 (0.88 for the pregnancy class and 0.68 for the nonpregnancy class). Precision for the pregnancy class was 0.93, and recall was 0.84. Feature analysis showed that the combination of dense and sparse vectors for classification achieved optimal performance. Employing the trained classifier resulted in the identification of 71,954 users from the collected posts. Over 250 million posts were retrieved for these users, which provided a multitude of longitudinal information about them. Conclusions: Social media sources such as Twitter can be used to identify large cohorts of pregnant women and to gather longitudinal information via automated processing of their postings. Considering the many drawbacks and limitations of pregnancy registries, social media mining may provide beneficial complementary information. Although the cohort sizes identified over social media are large, future research will have to assess the completeness of the information available through them.

/pdf/discovering-cohorts-of-pregnant-women-from-social-media-for-8i0arny6hp.pdf

Discovering Cohorts of Pregnant Women From Social Media for Safety Surveillance and Analysis.

Social media sites (e.g., Twitter) have been used for surveillance of drug safety at the population level, but studies that focus on the effects of medications on specific sets of individuals have had to rely on other sources of data. Mining social media data for this in-formation would require the ability to distinguish indications of personal medication in-take in this media. Towards that end, this paper presents an annotated corpus that can be used to train machine learning systems to determine whether a tweet that mentions a medication indicates that the individual posting has taken that medication at a specific time. To demonstrate the utility of the corpus as a training set, we present baseline results of supervised classification.

/pdf/detecting-personal-medication-intake-in-twitter-an-annotated-3tain47lpy.pdf

Detecting Personal Medication Intake in Twitter: An Annotated Corpus and Baseline Classification System

: Assurance cases provide an argument and evidence explaining why a claim about some system property holds. This report outlines a framework for justifying confidence in the truth of such an assurance case claim. The framework is based on the notion of eliminative induction - the principle (first put forward by Francis Bacon) that confidence in the truth of a hypothesis (or claim) increases as reasons for doubting its truth are identified and eliminated. Possible reasons for doubting the truth of a claim (defeaters) arise from analyzing an assurance case using defeasible reasoning concepts. Finally, the notion of Baconian probability provides a measure of confidence based on how many defeaters have been identified and eliminated.

/pdf/toward-a-theory-of-assurance-case-confidence-434eonfrw8.pdf

Ari Z. Klein

Papers

Overview of the Sixth Social Media Mining for Health Applications (#SMM4H) Shared Tasks at NAACL 2021

Discovering Cohorts of Pregnant Women From Social Media for Safety Surveillance and Analysis.

Detecting Personal Medication Intake in Twitter: An Annotated Corpus and Baseline Classification System

Toward a Theory of Assurance Case Confidence

Social media mining for birth defects research: A rule-based, bootstrapping approach to collecting data for rare health-related events on Twitter.