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Arkady B. Khodursky
Researcher at University of Minnesota
Publications - 61
Citations - 6681
Arkady B. Khodursky is an academic researcher from University of Minnesota. The author has contributed to research in topics: Gene & Escherichia coli. The author has an hindex of 29, co-authored 58 publications receiving 6114 citations. Previous affiliations of Arkady B. Khodursky include Stanford University & University of California, Berkeley.
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Global analysis of mRNA decay and abundance in Escherichia coli at single-gene resolution using two-color fluorescent DNA microarrays
TL;DR: The results identify previously unsuspected features of mRNA decay at a global level and also indicate that generalizations about decay derived from the study of individual gene transcripts may have limited applicability.
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Comparative gene expression profiles following UV exposure in wild-type and SOS-deficient Escherichia coli.
TL;DR: The time courses of expression of the genes surrounding the 26 documented lexA-regulated regions on the E. coli chromosome are reported here and several newly identified UV-responsive genes are discussed with respect to their possible roles in cellular recovery following exposure to UV irradiation.
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Persisters: a distinct physiological state of E. coli.
TL;DR: Bacterial populations contain persisters, phenotypic variants that constitute approximately 1% of cells in stationary phase and biofilm cultures as discussed by the authors, and multidrug tolerance of persisters is largely responsible for the inability of antibiotics to completely eradicate infections.
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Topoisomerase IV is a target of quinolones in Escherichia coli
TL;DR: The results imply that the quinolone binding pockets of gyrase and topo IV are similar and that substantial levels of drug resistance require mutations in both enzymes.
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Nitrogen regulatory protein C-controlled genes of Escherichia coli: Scavenging as a defense against nitrogen limitation
Daniel P. Zimmer,Eric Soupene,Haidy Lee,Volker F. Wendisch,Arkady B. Khodursky,Brian J. Peter,Robert A. Bender,Sydney Kustu +7 more
TL;DR: Nearly 2% of the E. coli genome appears to be under NtrC control, although transcription of some operons depends on the nitrogen assimilation control protein, which serves as an adapter between Ntr C and final sigma(70)-dependent promoters.