A
Armin Hinterwirth
Researcher at University of California, San Francisco
Publications - 30
Citations - 518
Armin Hinterwirth is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Azithromycin. The author has an hindex of 9, co-authored 21 publications receiving 223 citations.
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Journal ArticleDOI
Gut microbiome alteration in MORDOR I: a community-randomized trial of mass azithromycin distribution
Thuy Doan,Armin Hinterwirth,Lee Worden,Ahmed M. Arzika,Ramatou Maliki,Amza Abdou,Salissou Kane,Lina Zhong,Susie Cummings,S Sakar,Cindi Chen,Catherine Cook,Elodie Lebas,Eric D. Chow,Irving Nachamkin,Travis C. Porco,Jeremy D. Keenan,Thomas M. Lietman +17 more
TL;DR: Mass antibiotic administration to preschool children in Nigerien communities alters the relative abundances of 35 bacterial species in the gut microbiome, including enteric pathogens, but also increases expression of macrolide resistance genes.
Journal ArticleDOI
Macrolide and Nonmacrolide Resistance with Mass Azithromycin Distribution.
Thuy Doan,Lee Worden,Armin Hinterwirth,Ahmed M. Arzika,Ramatou Maliki,Amza Abdou,Lina Zhong,Cindi Chen,Catherine Cook,Elodie Lebas,Kieran S O'Brien,Catherine E. Oldenburg,Eric D. Chow,Travis C. Porco,Marc Lipsitch,Jeremy D. Keenan,Thomas M. Lietman +16 more
TL;DR: This trial showed that mass azithromycin distributions may propagate antibiotic resistance, including resistance to beta-lactam antibiotics, an antibiotic class prescribed frequently in this region of Africa.
Journal ArticleDOI
Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial.
Catherine E. Oldenburg,Benjamin A. Pinsky,Jessica M Brogdon,Cindi Chen,Kevin Ruder,Lina Zhong,Fanice Nyatigo,Catherine Cook,Armin Hinterwirth,Elodie Lebas,Travis Redd,Travis C. Porco,Thomas M. Lietman,Benjamin F. Arnold,Thuy Doan +14 more
TL;DR: Azithromycin has been hypothesized to have activity against SARS-CoV-2 infection in outpatients with COVID-19 symptoms at day 14 as mentioned in this paper, and the trial was terminated by the data and safety monitoring committee for futility after the interim analysis.
Journal ArticleDOI
Macrolide Resistance in MORDOR I - A Cluster-Randomized Trial in Niger.
Thuy Doan,Ahmed M. Arzika,Armin Hinterwirth,Ramatou Maliki,Lina Zhong,Susie Cummings,Samarpita Sarkar,Cindi Chen,Travis C. Porco,Jeremy D. Keenan,Thomas M. Lietman +10 more
TL;DR: In MORDOR I, azithromycin decreased mortality in children in Niger and was shown to have increased antimicrobial resistance in women.
Journal ArticleDOI
Association of Ocular Inflammation and Rubella Virus Persistence.
John A. Gonzales,Armin Hinterwirth,Jessica G. Shantha,Kaidi Wang,Lina Zhong,Susie Cummings,Ying Qian,Michael R. Wilson,Nisha R. Acharya,Thuy Doan +9 more
TL;DR: Findings suggest that persistent RV infection is associated with recurrent or chronic anterior or anterior-intermediate uveitis as well as corneal endothelial cell damage, and ophthalmologists should consider RV infection as a potential cause of hypertensive anterior and intermediate uveita.