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Arnaud Le Rouzic
Researcher at Université Paris-Saclay
Publications - 67
Citations - 2242
Arnaud Le Rouzic is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Population & Selection (genetic algorithm). The author has an hindex of 23, co-authored 62 publications receiving 1953 citations. Previous affiliations of Arnaud Le Rouzic include Uppsala University & University of Paris-Sud.
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Differential Metabolic Sensitivity of Insulin-like-response- and mTORC1-Dependent Overgrowth in Drosophila Fat Cells
Maelle Devilliers,Damien Garrido,Mickael Poidevin,Thomas Rubin,Arnaud Le Rouzic,Jacques Montagne +5 more
TL;DR: Drosophila genetics is used and differential metabolic sensitivity of mTORC1- and Ilp-dependent overgrowth is revealed, suggesting that local metabolic defects may elicit compensatory pathways between neighboring cells, whereas enzyme knockdown in the whole organism results in animal death.
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Gene network simulations provide testable predictions for the molecular domestication syndrome
TL;DR: The authors explored theoretically the effect of domestication at the genomic level by characterizing the impact of a domestication-like scenario on gene regulatory networks and showed that domestication profoundly alters genetic architectures.
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Detecting directional epistasis and dominance from cross-line analyses in Alpine populations of Arabidopsis thaliana
TL;DR: In this paper , the authors explored the contribution of dominance and epistasis in natural Alpine populations of Arabidopsis thaliana, for two fitness-related traits, the dry weight and the number of siliques.
Reconstructing the Evolutionary History of Transposable
Arnaud Le Rouzic,Thibaut Payen +1 more
TL;DR: It is demonstrated that it is possible to estimate the past transposition rate of a TE family, as well as how this rate varies with time, using statistical models developed to infer speciation and extinction rates in species phylogenies.
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Correlated stabilizing selection shapes the topology of gene regulatory networks
TL;DR: Simulations showed that correlated mutational effects evolved in both genetic architecture as a response to correlated selection, but the response in gene networks was less precise due to the mechanistic constraints of gene regulation.