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Arne K. Sandvik

Researcher at Norwegian University of Science and Technology

Publications -  203
Citations -  6565

Arne K. Sandvik is an academic researcher from Norwegian University of Science and Technology. The author has contributed to research in topics: Gastrin & Histamine. The author has an hindex of 44, co-authored 194 publications receiving 6060 citations. Previous affiliations of Arne K. Sandvik include University of Liverpool & University of the Sciences.

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A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control

TL;DR: Radioimmunoassay demonstrated ghrelin-like material in the rat oxyntic mucosa with moderate amounts also in antrum and duodenum and small amounts were found in the distal intestines and pancreas.
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Marked increase in gastric acid secretory capacity after omeprazole treatment.

TL;DR: Increased acid secretion after a conventional treatment period with a proton pump inhibitor is probably due to ECL cell hyperplasia and may have negative consequences for acid related diseases.
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Gastrin-histamine sequence in the regulation of gastric acid secretion.

TL;DR: This work has shown that both somatostatin2' and the prostaglandin E1 analogue misoprostolF' inhibit gastrin induced histamine release and acid secretion as well as histamine stimulated acid secretion, suggesting that somatOSTatin release could explain the inhibitory effect of gastrin release.
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Gastrin Produces an Immediate and Dose-Dependent Histamine Release Preceding Acid Secretion in the Totally Isolated, Vascularly Perfused Rat Stomach

TL;DR: It is shown that gastrin induces vascular histamine release of such a magnitude that this substance could be the mediator of the gastrin effect on acid secretion.