Arno Lukas

TL;DR: It is demonstrated for the first time that CsA-induced stress is not directly linked to its primary pharmacology, and the power of integrated omics for the elucidation of signaling cascades brought about by compound induced cell stress is demonstrated.

TL;DR: MMTV displays the most random dispersion of integration sites among retroviruses determined so far, and not even a modest tendency in favor of integration within genes was observed.

TL;DR: Cancer PINs representing differentially regulated genes are larger than those of randomly selected protein lists, indicating functional dependencies among protein lists that can be identified on the basis of transcriptomics experiments, but the prevalence of hub proteins was not increased in the presence of cancer.

TL;DR: This work presents a computational method to automatically select and rank peptides for the stimulation of potentially protective or otherwise functionally altering antibodies and shows that integration of variability, post-translational modification pattern conservation and B-cell antigenicity improve rational selection over random guessing.

TL;DR: This review summarizes protein markers discussed in the context of ARF as well as CKD, and provides an overview on currently available discovery results following ‘omics’ techniques.