Johannes Söllner

TL;DR: This work provides a comprehensive in vivo antigenic profile of Staphylococcus aureus, an important human pathogen, and makes use of whole genome sequence information, which has the potential to greatly accelerate and facilitate the formulation of novel vaccines.

TL;DR: By developing common datasets, standardized data formats, and the means with which to consolidate information, it is hoped to greatly enhance the development of B‐cell epitope prediction tools.

TL;DR: Structural as well as physicochemical parameters have been utilized for predicting the antigenic propensity of protein sites and the performance of computational routines has been low when compared to experimental alternatives.

TL;DR: MMTV displays the most random dispersion of integration sites among retroviruses determined so far, and not even a modest tendency in favor of integration within genes was observed.

TL;DR: In vitro protein selection, not biased by the context of living entities, allows screening of genomic expression libraries with a large number of different ligands simultaneously, and is a powerful approach for fingerprinting the repertoire of immune reactive proteins serving as target candidates for active and passive vaccination against pathogens.